Picking of genetic acne. In night also?

I've searched it almost thousands of time on the internet. Every where it is written one should not pick one's pimple or acne but no one ever told or perhaps no one ever asked that what should one do if the genetic acne burst with huge amount of pus automatically while washing face, laughing, opening mouth etc? 1) Should i just clean the pus which came out? 2) Should i try to take out the root of the cystic acne by pressing and sqeezing it? 3) Should i apply any kind of medicine or ointment? 4) Should i rush to the doctor? & what if i have lots of cystic acne on my face? Should i rush each and every time? What if it burst during night? Should i run each time to the doctor in night also? I'm so much surrounded by these questions. Please help me.