Osteoarithritis both knees. Medicine.

My mom is having osteoarthiritis both knee XRay Both knee AP And Lateral view Marginal patellar& central osteophytosis is seen bilaterally. Medial tibiofemoral & patellofemoral joint space are reduced. Subchondral sclerosis is noted. Para articular soft tissues are within normal limit Imp- osteoarthiritis both knee joints LFT, KFT, CBC ESR, Thyroid profile, RA factor 8,CRP 5 are above test Normal. ,Vit b12- 521,Vit D 47.3,Anti CCP 1.60. Dr gave her Jointace DN which cause heavy gas Nausea loose motion. Dr changed to Cartigen forte then Cartigen duo all these cause heavy gas nausea while taking PPI with emset . Now Dr suggest to take Adesam 400 OD for 3 month. I read it was liver medicine or work in osteoarthritis too. Plz suggest any better supplement for joint cartilage with no nausea gas sideffects. Can Adesam 400 will help Or not plz suggest I'm to worried now any good nutritonal supplement plz suggest plz help mom age is 45.weight 64 kg. Plz suggest any good medicine.