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Methotrexate effect on liver
Hello,
My mom is 58yrs old. She is suffering from Rheumatoid arthritis and on methotrexate for 12 yrs. She quaterly have her tests for CBC, ESR, SGPT, Creatine and crp.
Her SGPT is mostly normal, creatine recently at lower allowable limit and crp is some where around 35 since a year. She is having little pain while walking, but she manages that much.
My question is... Can she have methotrexate side effects on liver if she is having SGPT normal?? Or should we conduct some more liver tests to ensure her liver is perfectly fine??
Answers (1)
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Dr. Sakshi Mittal
Rheumatologist
11 yrs exp
Delhi
If her liver function tests are mostly normal, then that is all that is needed for monitoring methotrexate effects on liver in rheumatoid arthritis patients. Also, if her CRP is high that means she has ongoing inflammation in her joints. So even if she doesn't have much pain, her joints can still get damaged leading to deformities
Next Steps
Consult a Rheumatologist (arthritis specialist) for proper management of her rheumatoid arthritis
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.