bones-icon
High Esr but negative RF,CRP & Anti-Ccp
My sister is facing some joint pain in knees from sometime so she had a comprehensive arthritis profile test in which esr was high 42mm ( normal is 0-12) but rest other aspects like RF, Anti - CCP and CRP was negative. I would like to ask the reason of high Esr. What can be the cause ? Also her heamglobin is 11.4(normal 12-16) , eosinophil 0.90 ( normal is 1-7) and RDW - CV is 17.6 ( normal is 11-16).  Pls advice. Also can she have arthritis if only esr is high?
680 Views v

Answers (3)

20000+ health queries resolved in last month
Care AI Shimmer
There is something called as seronegative Arthritis in which RF and Anti CCP can be negative. Her Clincal examination is very important. Blood investigations are only supportive.
Next Steps
Meet a Rheumatologist
Answered
Flag this Answer
Flag this answer
Let others know if this answer was helpful
Was this answer helpful?
What is her age? It can be any Arthritis or can not be. History is important than the blood reports. Only raised ESR, without relavent history is not suggesting Arthritis
Next Steps
pls consult some Rheumatologist
Answered
Flag this Answer
Flag this answer
1/1 people found this helpful
Was this answer helpful?
Hello , First of all , high ESR will never cause arthritis. Its a non specific marker of inflammation which can be raised in lots of disorders . In some patients and that too especially in females sometimes high esr is normal finding . As regards your patients knee joint pain , a x ray and a thorough examination will help us understand more abt the issue . Anyhow , unless she has some immune related arthritis which she doesnt seem to have , osteoarthritis at her age is very rare. I would suggest to apply some ice packs , start any anti inflammatory medicine and physiotherapy in form of quadriceps and hamstring exercises
Next Steps
Observe , consult online
Answered
Flag this Answer
Flag this answer
1/1 people found this helpful
Was this answer helpful?
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.