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HBA2 related
Hi Doctors,
My wife HBA2 is high when HPLC is done. Now I have done HPLC test and result in underway. If the result is same for me then what is the best way to ensure that the baby will not be born with thalassemia. Please help. Currently planning for a baby.
Answers (8)
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If husband is also thalassemia minor , then there is a 25% chance that baby will have.
You can do prenatal genetic testing and selective embryo transfer via IVF
Or NIPT/ amniocentesis for the baby at 14 weeks pregnancy.
If husband is negative, nothing needs to be done.
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It depends on the severity
Wait for your reports
To prevent it go for a pgt
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Wait for ur result. Kindly update ur result, and then have a preconception al counseling,don't bother too much..will go step by step approach
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Higher HBA2 percentage depicts thalassemia minor/major. So next step is partners HPLC for knowing the risk to the fetus. If both are thal minor/ one of you is major then you have to go for amniocentesis for the baby for further testings.
If at all only one of is thal minor then only concern will be mother will be anemic and had to take supplements regularly
Better to start on
Tab FOLIC ACID 5mg once a day
Thank you
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Either conceive and then go for amniocentesis or IVF - PGT if u want to select embryo before transfer
Next Steps
wait for ur result and report and counsel
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Dr. Aastha Jain
Obstetrics & Gynecology
3 yrs exp
Ajmer
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Dr. Neha Vashisth
Obstetrician
12 yrs exp
Jaipur
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Dr. Prateeksha B S
Obstetrician
7 yrs exp
Bangalore
It depends if both of you are carrier or have minor severity of the condition.
Once you get the result get a genetic counseling done
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.