Estrogen pills and periods. Any issue!

I had my hysterolaproscopy on April 23.I am taking estrogen pills 2 mg twice a day due to adhesion removal via hysteroscopy.I had spotting around day 20 after taking estrogen pills.On May 15 I visited my doctor and had a follow up scan on which endometrium was 8.2.Doctor advised to take Primolut N 5mg thrice a day along with estrogen pills.I was also given Lupron depot 11.25 for my upcoming embryo transfer.I missed estrogen pills for 3 days then i resumed taking it until May 21.Today is day 4 after taking estrogen and primolut and I am waiting for my periods.I had light brown discharge from today morning but no full flow.Dr said that I will get a period around day 3 or day 4 after stopping medicines.pls advise whether missing my estrogen pills from May 16 to May 18 will cause any issue Thanks in advance