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Concerned for possible HLH
This must be the most wierdest question here as it is not actually about myself but I may be affected. So here it is Iam about go get married to a girl 23Yrs old who says she doesn't have any medical history my only concern is that her parents are cousins and she has a younger brother who is 9 yrs younger to her and was diagnosed with HLH few years back and subsequently got treated for it and now doing fine. I have read HLH in children is mostly familial and inherited from parents and there are 25% chances of sibling being carrier's😕. Now this makes me think and concerned that my so to be wife can also be a carrier thus putting our future child at risk. Iam not sure whether Im suppose to worry about it or not. I can surely use an experts opinion on this. Much appreciate.
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You need to meet a Medical Genetic specialist in this regard
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HLH may be inherited in an autosomal recessive manner or it can have non-genetic causes in which case it is called acquired HLH. There are five subtypes of inherited HLH which are designated as familial HLH, types 1-5. Each subtype is caused by a change (mutation) in a different gene. The genetic cause of type 1 is currently unknown. Types 2-5 are caused by mutations, testing is available. Can go for it for your to be wife.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.