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Biopsy? Cirrhosis
71 years, early cirrhosis, asymptomatic. Dr said ?AIH , ?PBC, or metabolic. Has prediabetes, hypertension. Osteoarthritis.  CHILD A.  Meld 8.  Fibrosis scan CAP mean 188, 31 kpa. ANA+. High IgG.  Liver enzymes were elevated earlier but after 2 months and changed to healthy diet repeat liver enzymes were less elevated. No ascites/jaundice. Mild pedal edema. 1) Is it absolutely necessary or worthwhile to do biopsy or endoscopy considering her age to rule out cause? 2) If autoimmune suspected and is not ready to take steroids as side effects are more serious, then is biopsy still required? 3) LFT r better than earlier. Does it mean she can get better? Is repeat ANA , IgG to b done?
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Biopsy is must for diagnosis and prognostication There are more effective medications than steroids to treat AIH No need for endoscopy Can be started on beta blockers after reports
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Biopsy is mandatory Steroids are mandatory for induction LFt will be changing in autoimmune hepatitis
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Biopsy will help in diagnosis Endoscopy for staging of disease There are other option available apart from steroids LFT used to fluctuate in Autoimmune hepatitis
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