The repeated low
sugar episodes around noon are most likely related to glimepiride, especially at 72 years of age. Metformin alone usually does not cause hypoglycemia. The fact that her sugars are sometimes high in the morning but drop significantly before lunch can occur with sulfonylurea treatment.
Her
diabetes treatment may therefore need adjustment to avoid further hypoglycemic episodes. The urinary complaint should also be evaluated separately, as difficulty passing urine or reduced urine flow can be due to UTI, urinary retention, dehydration or bladder dysfunction.
Next Steps
If you are taking glimepiride 1 mg, please discuss reducing or stopping it with your treating doctor rather than continuing the same dose despite recurrent low sugars.
Check fasting, pre-lunch and 2-hour post-meal glucose for a few days.
HbA1c, serum
creatinine/eGFR and
electrolytes should also be reviewed.
For the urinary symptoms, a urine routine/culture and ultrasound with post-void residual urine measurement would be useful to check for infection or incomplete bladder emptying.
Health Tips
If the
sugar is below 70 mg/dL, take 15 g of fast-acting carbohydrate such as glucose or sugar water and recheck after 15 minutes.
At her age, preventing recurrent hypoglycemia is more important than achieving very tight sugar control. If she develops confusion, excessive drowsiness, seizures or is unable to take food orally during a low-sugar episode, seek emergency medical care immediately.