You didn't mention the age of your wife. But I suppose it should be 40-45 years.
At this age, a D&C and sonography are a must before we proceed further. And so many other investigations will have to be done to get an idea about general health of the patient.
Next Steps
Please consult a Gynaecologist on Practo with all the details and investigations that you have. We can build up the case from that.
No short cut solutions.