You can be suffering from resistant depression, you can be helped by new generation antidepressants like desvenlafaxine, lamotrigine, vilazodone

Hello dear. As per your description it is likely you are suffering from a depressive disorder. As your psychiatrist has been looking after you for quite sometime now he will be a better judge for your medication needs. Howsoever, what you can do at your end is practice healthy lifestyle. 1.exercise daily- not just releases happiness producing chemicals, but also improves concentration, memory, stamina. 2.meditate daily- relaxation , pranayaam goes a long way in anxiety, mood management. 3. Eat & sleep healthy. 4.engage in social activities, recreational stuff despite being busy or not finding it interesting. Hope this helps hood luck!