Thank you for your question. Living with bipolar insomnia can indeed be extremely challenging, and it's encouraging to hear that Dayvigo (lemborexant) worked well for you. Dayvigo is a dual orexin receptor antagonist and is approved for long-term use. Clinical trials have demonstrated its safety and efficacy even beyond 6–12 months. However, in patients with bipolar disorder, long-term use needs individualized assessment—especially considering potential interactions with mood stabilizers and the risk of destabilizing mood cycles. 💡 Important to remember: Insomnia in bipolar disorder is not just a sleep issue—it can also precipitate mood episodes, so optimizing both sleep and mood stability is essential.

Thank you for your question. It's not uncommon for individuals with bipolar disorder to struggle with chronic insomnia. Dayvigo (lemborexant), an orexin receptor antagonist, is approved for long-term use in insomnia, including cases with underlying mood disorders, but it must be used cautiously in bipolar disorder due to the risk of mood destabilization. Since you report Dayvigo is the only agent that has consistently helped, long-term use may be considered- but only under close psychiatric supervision, ideally along with a mood stabilizer (like lithium, valproate, or lamotrigine), to prevent manic or hypomanic switches.

Current evidence suggests it is safe for long term use

Hello, thank you for sharing your concern. Dayvigo (lemborexant) is a relatively new sleep medication that works by regulating the brain’s wake-sleep cycle. Please consult your psychiatrist to discuss the risks and benefits of continued use and explore an integrated approach for sustained sleep and mood stability. It may also be worth exploring a long-term plan — which could include a combination of medication and psychotherapy.

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Hi.. you can consider following sleep hygiene techniques and may be try melatonin. Consult online for further evaluation and management

Take therapy along with it

Long term studies are not available as such. I hope you are taking it under doctors recommendation, as long as you are doing that and being monitored there is no problem

Maintain Sleep hygiene

Thank you for reaching out and sharing your concern. I understand how challenging bipolar-related insomnia can be, especially when sleep feels dependent on one particular medication like Dayvigo (lemborexant). Dayvigo is approved for treating insomnia and has been shown to be effective in the short and long term in clinical trials. However, in the context of bipolar disorder, long-term use of any sleep aid should be carefully monitored — particularly to avoid triggering mood episodes or developing dependence. Since you've experienced a return of insomnia after stopping Dayvigo, it’s important to reassess your overall treatment plan — including mood stability, sleep hygiene, and adjunct options. I’d strongly recommend a detailed consultation with me so I can evaluate your current condition and guide you on the safest and most effective long-term approach tailored to your needs. Feel free to book a session at your convenience.