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Blood test variation
Hello doctors,
When taking blood test anytime, WBC count and platelets is always high.
Recent blood test result:
Wbc- 14.3
Platelet- 470
Consulted multiple doctors but it's told no issues and no treatment is needed now. But I am still worried on it.
Please suggest what can be done.
Answers (12)
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High without symptoms so how n what treatment a doctor suggest.
Go for crp, esr
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For a 29-year-old female with consistently elevated WBC (14.3 × 10⁹/L) and platelet count (470 × 10⁹/L), based on the Harrison’s Manual of Medicine:
Interpretation:
Leukocytosis (WBC >11 × 10⁹/L):
Mild elevation like 14.3 is usually due to:
Chronic infections (e.g., TB)
Chronic inflammatory states
Stress or smoking
Drug effect (e.g., steroids)
Myeloproliferative disorders are rare but should be ruled out if persistentHARRISONS-Manual-of-Med….
Thrombocytosis (Platelets >350 × 10⁹/L):
If platelet count is persistently >450 × 10⁹/L, consider:
Reactive causes: infection, inflammation, iron deficiency, recent surgery, vitamin B12 deficiency, recovery from marrow suppression
Primary thrombocytosis (e.g., essential thrombocythemia) is a diagnosis of exclusion, usually when count >500 × 10⁹/L with no reactive causeHARRISONS-Manual-of-Med….
Next steps:
Repeat CBC in a few weeks to confirm persistent elevation.
Peripheral smear to look for reactive vs clonal features.
Rule out: iron deficiency, infection, inflammation.
If persistent and unexplained, bone marrow biopsy and JAK2 mutation testing may be considered to evaluate for a myeloproliferative disorderHARRISONS-Manual-of-Med….
There is no immediate danger if asymptomatic, but periodic monitoring and basic workup are advised.
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