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R Cin 450 mg Capsule

Manufactured byLupin Ltd.
ContainsRifampicin
Description
R Cin 450 mg Capsule is an antibiotic that is used to treat tuberculosis (a bacterial infection that affects your lungs) and meningitis (swelling of the protective layers of your brain and spinal cord) caused by bacteria. It prevents the bacteria from growing, thus it helps in treating the infection. R Cin 450 mg Capsule might cause some side effects like nausea, vomiting, headache, heartburn, etc., that subside with time. Avoid consuming alcohol while you are on treatment with this medicine because it may cause excessive drowsiness. Inform your doctor if any of the side effects become severe or persist for a long time. R Cin 450 mg Capsule may cause discolouration (yellow, orange, red, brown) of your teeth, urine, sweat, sputum, and tears. Soft contact lenses may be permanently stained. This is normal and not harmful. R Cin 450 mg Capsule should be taken on an empty stomach or 2 hours after the meal as the food decreases its absorption. Your doctor will decide the dose and duration of this medicine based on the severity and location of the infection. Ensure to complete the entire course and do not stop taking it on your own. Stopping it early may make the infection reoccur and be difficult to treat. R Cin 450 mg Capsule should be used with caution if you have liver and stomach/intestinal disease. Inform your doctor about any other medications you are taking since a few may interact with or be impacted by this medication. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.

Side effects

Major & minor side effects for R Cin 450 mg Capsule

  • Heart burn
  • Headache
  • Nausea and Vomiting
  • Increased menstrual flow
  • Bloating
  • Dark colored urine
  • Dizziness

Uses of R Cin 450 mg Capsule

What is it prescribed for?

  • Tuberculosis
  • Meningococcal Meningitis
  • Leprosy
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    R Cin 450 mg Capsule starts to show its action in 1-3 hours. However, you may start feeling well in few days to weeks.
  • How long do the effects of this medicine last?
    The amount of time for which R Cin 450 mg Capsule remains for an average duration of 15 hours in your body.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid drinking alcohol while on treatment with R Cin 450 mg Capsule as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported for R Cin 450 mg Capsule.
  • Can this medicine be taken during pregnancy?
    R Cin 450 mg Capsule is not recommended for use if you are pregnant. It may cause affect your foetus; hence, consult your doctor before using it.
  • Can this medicine be taken while breast-feeding?
    R Cin 450 mg Capsule passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.

Allergy

If you have a known allergy to R Cin 450 mg Capsule, avoid this medication. Seek immediate medical attention if you notice any symptoms of allergic reactions such as a skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Anti viral medications

R Cin 450 mg Capsule is not recommended for use if you are receiving antiviral therapy. This medicine can decrease the effectiveness of antiviral medicines and may lead to viral resistance.

Sever liver impairment

R Cin 450 mg Capsule should be used with caution if you have any liver conditions. This medicine is metabolised in your liver, and improper liver function can lead to the accumulation of this medicine in your body. This may worsen your condition.
Warnings for special population

Pregnancy

R Cin 450 mg Capsule is not recommended for use if you are pregnant. It may cause affect your foetus; hence, consult your doctor before using it.

Breast-feeding

R Cin 450 mg Capsule passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.
General warnings

Diabetes

R Cin 450 mg Capsule should be used with caution if you have diabetes (a condition in which the blood sugar level increases). This medicine may alter your blood sugar levels and affect the management of diabetes.

Antibiotic-resistance

Usage of R Cin 450 mg Capsule without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of the development of bacteria that are drug-resistant.

Kidney impairment

R Cin 450 mg Capsule should be used with caution if you have any medical conditions affecting your kidneys. This medicine is metabolised in your liver and excreted through urine. Any kidney dysfunction can lead to its accumulation in your body. This may worsen your condition.

Use in children

R Cin 450 mg Capsule is not recommended for use in children and adolescents below 15 years of age due to the lack of safety and efficacy of its use.

Severe bleeding

R Cin 450 mg Capsule may cause bleeding. Vitamin K supplements may be prescribed by your doctor to prevent bleeding.

Missed Dose

If you have missed R Cin 450 mg Capsule dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take R Cin 450 mg Capsule more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid drinking alcohol while on treatment with R Cin 450 mg Capsule as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
Interaction with Medicine

Clopidogrel

Propranolol

Warfarin

Atorvastatin

Live cholera vaccine

Diltiazem

Cyclosporine

Disease interactions

Colitis

R Cin 450 mg Capsule should be used with caution if you have colitis [swelling of the colon (a part of the intestine)]. This medication may cause the infection to flare up, thus can worsen your condition.

Hematopoietic disturbances

Hematopoietic disturbances are disorders that primarily affect the blood & blood-forming organs like bone marrow. Take R Cin 450 mg Capsule with extreme caution as it may worsen your condition.

Porphyria

Porphyria is a blood disorder that is caused due to build-up of certain chemicals related to red blood cell proteins. Take R Cin 450 mg Capsule with extreme caution as it may worsen your condition.
Food interactions
R Cin 450 mg Capsule should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal because food decreases the absorption of this medicine.
Lab interactions
Information not available.
Take R Cin 450 mg Capsule on an empty stomach, either 1 hour before or 2 hours after a meal. The absorption of this medicine may be reduced if it is taken along with food. Consult the doctor if you experience any undesirable effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. It may cause discolouration (yellow, orange, red, brown) of your teeth, urine, sweat, sputum, and tears. Soft contact lenses may be permanently stained. This is normal and not harmful. This medicine may reduce the effects of oral contraceptives (medicines to prevent an unwanted pregnancy). Therefore, use effective preventive measures to avoid unwanted pregnancy.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
R Cin 450 mg Capsule acts by blocking the action of bacterial components, which is necessary for tuberculosis bacteria to produce vital proteins and multiply.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antituberculosis agents

Schedule

Schedule H

Drugs, H., 2021. Rifampin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 31 August 2021].

https://medlineplus.gov/druginfo/meds/a682403.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 24 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/050420s073,050627s012lbl.pdf>

Allen, H., 2021. Rifampicin. [online] Patient.info. Available at: <o/medicine/rifampicin-for-infection-rifadin-rimactane> [Accessed 24 August 2021].

https://patient.inf

Pharmacology, C., 2021. Patient Information Leaflet - Rifampicin - My Medicines. [online] Mymedicines.nz. Available at: < [Accessed 24 August 2021].

https://www.mymedicines.nz/home/sheet/F7P7ZNVU7hw=?format=inline>
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Information on this page was last updated on 15 Sep 2021

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.