Rifampicin

Description

Rifampicin is an antitubercular medicine which helps to treat tuberculosis and meningococcal meningitis. It should be taken with other medicines to prevent the spread of infection. This medicine may cause reddish colouration of the urine, sweat, sputum and tears.

Side effects

Major & minor side effects for Rifampicin

  • Abdominal pain
  • Dizziness
  • Headache
  • Yellow colored eyes or skin
  • Nausea and Vomiting
  • Skin rash
  • Loss of appetite
  • Unusual behavior
  • Muscle pain
  • Weakness

Uses of Rifampicin

What is it prescribed for?

  • Tuberculosis
  • Meningococcal Meningitis
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed in 2 to 4 hours.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 9 to 12 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
  • Usage while breast-feeding?
    This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.

Allergy

Not recommended in patients with known allergy to Rifampicin .

Antiviral medications

Not recommended in patients receiving antiviral therapy due to the decrease in the effect of antiviral medications.
Warnings for special population

Pregnancy

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding

This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver injury

This medicine may cause liver injury, therefore should be used with caution. The liver function tests should be performed before starting the treatment. The dose should be adjusted based on the severity of liver disease.

Diabetes

This medicine may alter the blood glucose levels. Inform the doctor about your medical condition before starting the treatment. Monitoring of blood glucose levels is necessary.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Missed Dose

If you miss a dose of Rifampicin , take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Propranolol

Warfarin

Atorvastatin

Disease interactions

Impaired liver function

Inform the doctor if you have liver disease before receiving this medicine. Close monitoring of liver function is necessary. Any signs of an increase in the liver enzymes should be informed to the doctor. The treatment should be stopped temporarily until the liver enzymes return to normal.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Rifampicin as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Do not stop taking the medicine without consulting your doctor. Ensure that the course of treatment is completed to prevent the spread of infection. Consult the doctor if you experience any undesirable effects
Miscelleneous

To be taken before food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by interfering with the bacterial DNA synthesis and stops the growth of the bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antituberculosis agents

Schedule

Schedule H

[Internet]. 2017 [cited 29 May 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/21221

DailyMed - Rifampin capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 29 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=55816042-946d-4bec-9461-bd998628ff45

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 29 May 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 29 May 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~mwlmqL:1

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Information on this page was last updated on 5 Jan 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.