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NovoMix 50 Penfill
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NovoMix 50 Penfill

Manufactured byNOVO NORDISK INDIA PVT LTD
ContainsInsulin Aspart (50 International units ) + Insulin Aspart Protamine (50 International units )
Description
NovoMix 50 Penfill is used for the treatment of diabetes mellitus (a condition with high blood sugar levels). This medicine is a combination of rapid-acting and intermediate-acting analogues of insulin that consistently works for several hours after injection and provides effective blood sugar control throughout the day. NovoMix 50 Penfill may result in low blood sugar levels, and you may feel hungry, irritable, dizzy, anxious or shaky. Consult your doctor if these symptoms persist or become severe. Avoid consumption of alcohol as it may lower your blood sugar levels. NovoMix 50 Penfill should be administered exactly as advised by your doctor. This medicine is injected under your skin. Take it at the same time every day to maintain a constant level of this medicine in your body. Do not skip doses or discontinue the treatment without consulting your doctor as it may cause an increase in your blood sugar levels. NovoMix 50 Penfill is not recommended if you are allergic to it. Inform your doctor if you have pre-existing liver or kidney problems. If you are pregnant or planning a pregnancy or breastfeeding, take this medication only if prescribed by your doctor.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for NovoMix 50 Penfill

  • Decreased blood glucose levels
  • Reaction at the injection site
  • Skin rash

Uses of NovoMix 50 Penfill

What is it prescribed for?

  • Type I Diabetes mellitus
  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    NovoMix 50 Penfill begins to show its effect within 15 minutes after administration.
  • How long do the effects of this medicine last?
    The effect of NovoMix 50 Penfill lasts for an approximate duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with NovoMix 50 Penfill as it may alter your blood sugar levels. This may cause side effects such as dizziness, drowsiness, increased thirst, increased hunger, mood changes, extreme fatigue, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies have been reported with NovoMix 50 Penfill.
  • Can this medicine be taken during pregnancy?
    NovoMix 50 Penfill is not known to affect your developing foetus when taken during pregnancy. Hence this medicine may be safe to use during pregnancy upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    NovoMix 50 Penfill passes into breastmilk and is not known to cause side effects in your infant. Hence this medicine may be safe to use during breastfeeding upon your doctor's recommendation.

Allergy

Avoid taking NovoMix 50 Penfill if you are allergic to it. However, seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

NovoMix 50 Penfill is not known to affect your developing foetus when taken during pregnancy. Hence this medicine may be safe to use during pregnancy upon your doctor's recommendation.

Breast-feeding

NovoMix 50 Penfill passes into breastmilk and is not known to cause side effects in your infant. Hence this medicine may be safe to use during breastfeeding upon your doctor's recommendation.
General warnings

Diabetic Ketoacidosis

Diabetic ketoacidosis is a condition of increased levels of ketones (blood acids). NovoMix 50 Penfill is not recommended for the treatment of diabetic ketoacidosis. Your doctor will determine suitable treatment options based on your clinical condition.

Subcutaneous use only

NovoMix 50 Penfill is meant for subcutaneous administration (under the skin) only. The long duration of action of this medicine is dependent on a subcutaneous administration. It should not be administered intravenously (into the veins) or intramuscularly (into the muscles).

Hypoglycemia (Low blood sugar levels)

NovoMix 50 Penfill may cause low blood sugar levels. Hence, regular monitoring of your blood sugar levels is recommended. Your doctor may advise you to carry a sugar candy to counteract the effects of low blood sugar levels.

Use with other insulins

NovoMix 50 Penfill should not be diluted or mixed with any other insulin or solution as it may alter the effects of other insulins when administered together and/or increase the risk of side effects.

Allergic Reactions at the injection Site

Injection site reactions that may occur with NovoMix 50 Penfill include redness, pain, itching, swelling or hives (itchy, painful eruptions that sting). Continuous rotation of the injection site within a given area is recommended to help reduce or prevent these reactions. These reactions usually resolve within a few days to a few weeks.

Driving or operating machines

Your ability to drive vehicles or operate machines may be affected due to low or high blood sugar levels. Hence, avoid activities that require mental alertness if you experience any symptoms such as dizziness, blurred vision, etc. while taking this medicine.

Missed Dose

If you miss a dose of NovoMix 50 Penfill, contact your doctor for further instructions. You should not use more than one dose in a 24-hour period unless specifically instructed by your doctor.

Overdose

Seek immediate medical attention or contact your doctor if an overdose of NovoMix 50 Penfill is suspected. Hypoglycaemia (low blood sugar levels) may occur in case of an overdose with symptoms such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, dizziness, confusion, etc. In cases of mild hypoglycemic episodes, oral glucose or sugary products can be used to avoid severe hypoglycaemia.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with NovoMix 50 Penfill as it may alter your blood sugar levels. This may cause side effects such as dizziness, drowsiness, increased thirst, increased hunger, mood changes, extreme fatigue, etc.
Interaction with Medicine

Corticosteroids

Beta blockers

ACE inhibitors

Aspirin

Ciprofloxacin

Monoamine oxidase inhibitors (MAOIs)

Disease interactions

Kidney/Liver Disease

NovoMix 50 Penfill should be used with caution if you have pre-existing kidney/liver problems due to the increased risk of severe side effects.

Hypokalaemia

NovoMix 50 Penfill may increase your risk of hypokalaemia (low blood potassium levels). Your blood potassium levels need to be closely monitored while on treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Carefully follow all the instructions given by your doctor. Do not administer NovoMix 50 Penfill in larger or smaller amounts than prescribed. Administer NovoMix 50 Penfill 15 minutes before your meal. However, for type 2 diabetes, the dose may also be taken after the meal. Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. Avoid the use of this medicine if the solution is cloudy, coloured or contains solid particles. Avoid the discontinuation of this medicine without consulting your doctor as it may increase your blood sugar levels. Regular monitoring of blood sugar levels and frequent follow-up visits with your doctor is recommended so that your doctor can evaluate your condition.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
NovoMix 50 Penfill is a modified form of insulin that works similarly to human insulin. It improves blood sugar control by enhancing glucose uptake from the blood into body tissues and also by preventing the production of glucose in the liver.
Legal Status

Unknown

Approved

Unknown

Unknown

Classification

Category

Insulin, Insulin analogue combination, Antidiabetic agents

Schedule

Schedule G

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https://www.medicines.org.uk/emc/product/1600/smpc>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 2 December 2021].

https://www.medicines.org.uk/emc/files/pil.1600.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 2 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021810s015lbl.pdf>

Drugs, H., 2021. Insulin Aspart (rDNA Origin) Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 2 December 2021].

https://medlineplus.gov/druginfo/meds/a605013.html>

Ebs.tga.gov.au. 2021. TGA eBS - Product and Consumer Medicine Information Licence. [online] Available at: < [Accessed 2 December 2021].

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-02966-3>
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Information on this page was last updated on 3 Dec 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.