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Esozenam-IV

Manufactured byBIOZENESIS HEALTHCARE
ContainsEsomeprazole
Description
Esozenam-IV is an anti-ulcer medicine. It is used to treat conditions where the stomach produces too much acid. Stomach and duodenal ulcers, gastroesophageal reflux disease (a condition in which the stomach acid flows back into your food pipe), and erosive esophagitis (swelling of the food pipe) are certain problems caused by high levels of stomach acid. Esozenam-IV interferes with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased and the ulcer healing process is fastened. Common side effects of Esozenam-IV are nausea, vomiting, headache, stomach pain, and diarrhoea. Esozenam-IV is administered into your vein by a health care professional in a hospital or clinic. It is used for the short-term treatment of stomach and intestinal conditions when oral treatment is not possible or appropriate. Esozenam-IV is not recommended for use if you are allergic to it. Inform your doctor if you have liver or kidney problems, or any other health condition. Report all the medicines that you are taking to your doctor as they can interact with this medicine and reduce its effectiveness. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.

Side effects

Major & minor side effects for Esozenam-IV

  • Headache
  • Nausea or Vomiting
  • Excessive gas in stomach
  • Stomach pain
  • Skin rash
  • Swelling and redness at the injection site
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Irregular heartbeat
  • Diarrhoea
  • Unusual tiredness and weakness
  • Decreased appetite
  • Dizziness

Uses of Esozenam-IV

What is it prescribed for?

  • Gastroesophagal Reflux Disease
  • Gastric and duodenal ulcers
  • Erosive Esophagitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Esozenam-IV to show its effects is not clinically known.
  • How long do the effects of this medicine last?
    The time duration for which Esozenam-IV remains active in your body is not clinically determined.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Esozenam-IV.
  • Can this medicine be taken during pregnancy?
    Esozenam-IV is not recommended during pregnancy as not enough studies are done to understand its safety. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    It is not known if Esozenam-IV passes into breast milk. Therefore, if you are breastfeeding, consult your doctor to understand the risks and benefits associated with this medicine.

Allergy

Esozenam-IV is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.
Warnings for special population

Pregnancy

Esozenam-IV is not recommended during pregnancy as not enough studies are done to understand its safety. Consult your doctor if you are pregnant.

Breast-feeding

It is not known if Esozenam-IV passes into breast milk. Therefore, if you are breastfeeding, consult your doctor to understand the risks and benefits associated with this medicine.
General warnings

Hypomagnesaemia

Esozenam-IV may result in hypomagnesaemia (low magnesium levels in your blood) on prolonged use. Inform your doctor if you experience symptoms such as dizziness, irregular heartbeat, shivering, muscle pain, seizures (fits). Your doctor may monitor your magnesium levels at regular intervals during treatment with this medicine.

Lupus erythematosus

Lupus erythematosus is an autoimmune disorder that affects the skin, kidneys, brain, joints, and other organs. It occurs when the immune system of the body attacks its own tissues. Lupus may occur or get worse while you are receiving Esozenam-IV. Inform your doctor immediately if you experience tiredness, painful joints, rashes, or lesions on the skin during treatment with this medicine.

Missed Dose

Since Esozenam-IV is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since Esozenam-IV is administered in the hospital or clinical setting by a qualified healthcare professional, the chances of an overdose are very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Ketoconazole

Methotrexate

Warfarin

Nelfinavir

Digoxin

Disease interactions

Liver Disease

Esozenam-IV should be used with caution if you have liver problems. Impaired liver function may lead to an increase in the levels of unused medicine in your blood. Your doctor may adjust your dose or suggest another medicine in such cases.

Osteoporosis

Osteoporosis is a condition in which bones become weak and fragile (may break from a fall). Esozenam-IV can reduce bone density (thinning of bones). Hence, inform your doctor if you have osteoporosis before starting the treatment with this medicine.

Colitis

Esozenam-IV may cause diarrhoea. Hence, inform your doctor if you have stomach and intestine problems, particularly colitis (swelling of the inner lining of the colon), as it may cause severe diarrhoea.
Food interactions
Information not available.
Lab interactions
Information not available.
Esozenam-IV should be administered by a qualified healthcare professional in the clinical or hospital setting. Report any undesirable effects to your doctor immediately.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Esozenam-IV reduces the production of acid in the stomach. It stops the action of the proton pumps that are found on cells that line the stomach, which decreases stomach acid production.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Proton pump inhibitors, Anti-Ulcer Agents

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Esomeprazole. [online] Available at: < [Accessed 2 March 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Esomeprazole>

Drugs, H., 2021. Esomeprazole Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 2 March 2021].

https://medlineplus.gov/druginfo/meds/a619032.html>

Medicines.org.uk. 2021. Esomeprazole 40 mg powder for solution for injection/infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 March 2021].

https://www.medicines.org.uk/emc/product/11259/smpc>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 2 March 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021689s030lbl.pdf>
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Information on this page was last updated on 12 Nov 2021

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