Esomeprazole

Description

Esomeprazole is a proton pump inhibitor used in the treatment of stomach ulcers, Gastroesophageal reflux disease(GERD) and other acidity related disorders. It decreases the acid produced in the stomach and also helps in the healing of ulcers.

Side effects

Major & minor side effects for Esomeprazole

  • Headache
  • Nausea
  • Flatulence
  • Stomach pain
  • Skin rash
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Irregular heartbeat
  • Severe diarrhea
  • Unusual tiredness and weakness
  • Fever
  • Decreased appetite

Uses of Esomeprazole

What is it prescribed for?

  • Erosive Esophagitis
  • Gastroesophagal Reflux Disease
  • Helicobacter pylori Infection
  • Zollinger-Ellison Syndrome
  • Other forms of Ulcers
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within an hour of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 16-18 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine can be used by pregnant women only when necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use by breastfeeding women as it may cause some harm to the infant. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before taking this medicine.

Allergy

This medicine is not recommended for patients who are allergic to Esomeprazole or any other drug of the same group i.e Benzimidazoles.
Warnings for special population

Pregnancy

This medicine can be used by pregnant women only when necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use by breastfeeding women as it may cause some harm to the infant. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before taking this medicine.
General warnings

Diarrhea

This medicine has been associated with an increased incidence of Clostridium difficile associated diarrhea in some patients. Consult your doctor if you experience diarrhea that does not improve over time.

Liver disease

Report any incidence of liver disease to the doctor. This medicine is not recommended for use if the impairment is severe. For mild to moderate impairment, this medicine can be given with suitable dose adjustment and safety monitoring.

Immune system disorder

Use of this medicine for durations longer than medically recommended can cause skin disorders by affecting the immune system. Report any incidence of skin lesion formation to the doctor while using this medicine.

Risk of infections

Use of this medicine increases the susceptibility to infections from bacteria.

Bone fracture

Use of high dose of Esomeprazole for prolonged duration may increase the risk of bone fractures especially in older patients and women. Supplements like Calcium citrate and Vitamin D should be taken after consulting the doctor.

Vitamin B12 deficiency

Long-term treatment with Esomeprazole may decrease the absorption of Vitamin B-12 in the body. Supplements can be taken after consulting the doctor.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose should be skipped.

Overdose

Contact your doctor immediately if an overdose is suspected. Symptoms may include confusion, drowsiness, blurred vision, dry mouth, and headache.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Ketoconazole

Methotrexate

Warfarin

Nelfinavir

Digoxin

Disease interactions

Liver Disease

Report any incidence of liver disease to the doctor. Suitable adjustment in dosage might be needed based on the extent of the liver impairment

Osteoporosis

Suitable adjustment in dosage and duration should be made for patients who are at risk for Osteoporosis related fracture. Established treatment guidelines should be strictly followed in such cases.

Hypomagnesemia

Report any incidence of magnesium level imbalance in the body to the doctor. The imbalance could occur due to a disease or due to other medication used by the patient. Regular monitoring is recommended for patients taking Esomeprazole in such cases.
Food interactions
Information not available.
Lab interactions

Neuroendocrine tumor diagnosis

Report the use of Esomeprazole to the doctor before undergoing for the neuroendocrine/carcinoid tumor test. This medicine may give a false positive result for this diagnostic test.
Take Esomeprazole as instructed by the doctor. This medicine should be taken an hour before food. An adequate amount of water should be consumed with this medicine. Do not take this medicine for longer than the recommended duration.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Proton pump inhibitors

Schedule

Schedule H

DailyMed - Esomeprazole sodium injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27d8e920-932c-4ccb-9ad8-9c7b9e2e4385

Esomeprazole | C17H19N3O3S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 30 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/9568614

Esomeprazole: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a699054.html

[Internet]. 2017 [cited 16 November 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24915

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 14 Aug 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.