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Nexpro 40 MG Injection

Manufactured byTorrent Pharmaceuticals Ltd.
ContainsEsomeprazole
Description

Nexpro 40 MG Injection is a proton pump inhibitor used in the treatment of stomach ulcers, Gastroesophageal reflux disease(GERD) and other acidity related disorders in patients with damage to their esophagus or who are unable to take oral forms of esomeprazole. It is also used for preventing the bleeding of gastric or duodenal ulcers in adult patients followed by a therapeutic endoscopy.

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Side effects

Major & minor side effects for Nexpro 40 MG Injection

  • Headache
  • Nausea or Vomiting
  • Flatulence
  • Abdominal pain
  • Skin rash
  • Swelling and redness at the injection site
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Irregular heartbeat
  • Severe diarrhea
  • Unusual tiredness and weakness
  • Fever
  • Decreased appetite

Uses of Nexpro 40 MG Injection

What is it prescribed for?

  • Gastroesophagal Reflux Disease with Erosive Esophagitis
  • Gastric/Duodenal Ulcer Prophylaxis
  • NSAID-Induced Gastric Ulcer
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Esomeprazole, other benzimidazoles, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Diarrhea

Use of this medicine has been associated with an increased incidence of Clostridium difficile associated diarrhea in some patients. Report any such incidence to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver disease

This medicine should be used with caution in patients with severe liver disease due to the increased risk of adverse effects. Regular monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Immune system disorder

Use of this medicine for durations longer than medically recommended can cause skin disorders by affecting the immune system. Report any incidence of skin lesion formation to the doctor while using this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Bone fractures

Use of high dose of this medicine or for a prolonged duration may increase the risk of bone fractures, especially in older patients and women. Supplements like Calcium citrate and Vitamin D should be taken after consulting the doctor.

Vitamin B12 deficiency

Long-term treatment with this medicine may decrease the absorption of Vitamin B-12 in the body. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Ketoconazole

Methotrexate

Warfarin

Nelfinavir

Digoxin

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Osteoporosis

This medicine should be used with caution in patients with osteoporosis due to the increased risk of fractures of the hip, wrist, or spine. Appropriate corrective measures, dose adjustment, or replacement with a suitable alternative may be necessary based on the clinical condition.

Colitis

This medicine should be used with extreme caution in patients with colitis due to the increased risk of clostridium difficile-associated diarrhea. Appropriate corrective measures, dose adjustment, or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Proton pump inhibitors

Schedule

Schedule H

DailyMed - Esomeprazole sodium injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27d8e920-932c-4ccb-9ad8-9c7b9e2e4385

Esomeprazole | C17H19N3O3S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 30 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/9568614

Esomeprazole Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited 14 August 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a619032.html

Esomeprazole 40 mg powder for solution for injection/infusion. - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 14 August 2019]. Available from:

https://www.medicines.org.uk/emc/product/4095/smpc
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Information on this page was last updated on 14 Aug 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.