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Domadol 50 MG Injection

Manufactured byUnichem Laboratories Ltd.
ContainsTramadol
Description

Domadol 50 MG Injection is a painkiller belonging to a group of medicines known as opioid analgesics. It is used to relieve moderate to severe pain.

Side effects

Major & minor side effects for Domadol 50 MG Injection

  • Constipation
  • Pain at the injection site
  • Dizziness
  • Sense of imbalance
  • Headache
  • Sleepiness
  • Agitation and anxiety
  • Indigestion
  • Convulsions
  • Irregular heartbeat
  • Shortness of breath
  • Itching or rash
  • Nervousness

Uses of Domadol 50 MG Injection

What is it prescribed for?

  • Moderate to severe pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Mild to moderate habit forming tendencies have been reported and hence requires careful administration and withdrawal.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to tramadol or any other inactive ingredients present in the formulation.

Severe asthma and breathing problems

This medicine is not recommended for use in patients suffering from breathing difficulties which may be caused due to various conditions such as asthma, hypercapnia, etc. since it may worsen the patient's condition.

Gastrointestinal bleeding

This medicine is not recommended for use in patients with a known history of gastrointestinal bleeding due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.

Gastrointestinal obstruction

This medicine is not recommended for use in patients with gastrointestinal obstruction including paralytic ileus due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Drug dependence and abuse

This medicine has a high potential for addiction and abuse even at recommended dosages, especially with prolonged use. Appropriate patient monitoring, safety precautions, and management of dose quantity are recommended to reduce the risk of drug abuse.

Respiratory disorders

This medicine should be used with extreme caution in patients with respiratory disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypotension

The use of this medicine may cause a sudden drop in blood pressure, especially while getting up from a sitting or a lying position. Patients are advised to get up slowly from a sitting or a lying position to avoid fainting, dizziness, and falling. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Reduced fertility

Prolonged use of this medicine can reduce fertility in males and females in the reproductive age group. Patients should be informed about the potential effect on reproductive capabilities before beginning treatment with this medicine.

Acute abdominal conditions

This medicine should be used with caution in patients with acute abdominal conditions due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Suicidal tendencies

This medicine should be used with extreme caution in patients exhibiting suicidal tendencies due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

Elderly patients

This medicine should be administered with caution in elderly patients since the risk of severe adverse effects is significantly high. Suitable adjustments in dose quantity and safety monitoring may be required in such cases.

Use in children

This medicine is not recommended for use in patients less than 12 years of age since the safety and effectiveness of use are not clinically established.

Withdrawal symptoms

Abrupt withdrawal of this medicine may cause withdrawal symptoms. Withdrawal of this medicine should be undertaken gradually using a dosage-tapering schedule. Symptoms of withdrawal may include tremors, nausea and vomiting, chills and fever, diarrhea, and even hallucinations in some cases.

Driving or operating machinery

This medicine may cause dizziness, fainting, and drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amitriptyline

Fluoxetine

Ketoconazole

Ofloxacin

Warfarin

Codeine

Theophylline

Monoamine oxidase inhibitors

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizures

This medicine should be used with caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Respiratory Depression

This medicine should be used with caution in patients with a history of respiratory depression due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Intracranial pressure

This medicine should be used with caution in patients with increased intracranial pressure or head injury due to the risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine acts on the central nervous system and brain by changing the perception and response to the pain.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Narcotic analgesics

Schedule

Schedule H1

Tramadol - DrugBank [Internet]. Drugbank.ca. 2019 [cited 12 February 2019]. Available from:

https://www.drugbank.ca/drugs/DB00193

[Internet]. Who.int. 2020 [cited 6 March 2020]. Available from:

https://www.who.int/medicines/areas/quality_safety/6_1_Update.pdf

[Internet]. Medicines.org.uk. 2020 [cited 6 March 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.4454.pdf

Tramadol [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 6 March 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Tramadol
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Information on this page was last updated on 12 Mar 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.