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Cyclophil Me 100 mg Oral Suspension
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Cyclophil Me 100 mg Oral Suspension

Manufactured byBiocon Ltd.
ContainsCyclosporine
Description
Cyclophil Me 100 mg Oral Suspension is an immunosuppressant used in organ transplant patients, rheumatoid arthritis, and psoriasis. It should be used under the supervision of a qualified physician. Close monitoring of kidney function is necessary while taking this medicine.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Cyclophil Me 100 mg Oral Suspension

  • Decrease in blood cell count
  • Tremors
  • Headache
  • Nausea and Vomiting
  • Skin rash
  • Fever and chills
  • Abdominal discomfort
  • Facial hair growth
  • Running Nose

Uses of Cyclophil Me 100 mg Oral Suspension

What is it prescribed for?

  • Organ Transplant - Rejection Prophylaxis
  • Rheumatoid Arthritis
  • Psoriasis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. If the medicine is used, close monitoring of the infant for any undesired effects is necessary.

Allergy

This medicine is not recommended for use in patients with a known history of allergy to cyclosporine, cyclosporin, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. If the medicine is used, close monitoring of the infant for any undesired effects is necessary.
General warnings

Malignancy

This medicine may increase the risk of developing lymphoma and other malignancies in some patients, especially of the skin. Doctors should inform patients about these risks and advise the patient to prevent exposure to the sunlight by wearing protective clothing.

Serious infections

This medicine should be used with caution in patients who are at risk of developing serious infections since it suppresses the immune system and further increases the risk of infections. Any symptoms such as a sore throat, fever, chills, etc. should be reported to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Kidney impairment

This medicine is not recommended in patients with a history of kidney impairment. Close monitoring of kidney function is necessary. The dose should be adjusted based on the creatinine clearance (CrCl).

Hyperkalemia

This medicine may increase the levels of potassium in the body and may increase the risk of arrhythmia. Close monitoring of potassium levels is necessary while receiving this medicine. Medicines that can increase the potassium levels like ACE inhibitors and potassium-sparing diuretics should be avoided. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Hypertension

This medicine should be used with extreme caution in patients suffering from elevated blood pressure due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amlodipine

Live attenuated vaccines and related products

Citalopram

Gefitinib

Ibuprofen

Diclofenac

Disease interactions

Kidney Disease

This medicine is not recommended for use in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended while receiving this medicine as it may increase this medicine's concentration and increase the risk of liver and kidney injury. It is advised to consult the doctor for a proper diet management before receiving this medicine.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. It is advised to take this medicine at the same time every day. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by decreasing the body's immune system activity and helps in preventing the body's rejection action of transplanted organs.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Calcineurin inhibitors

Schedule

Schedule H

Cyclosporine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 June 2017]. Available from:

https://www.drugbank.ca/drugs/DB00091

Neoral Oral Solution - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 23 April 2020]. Available from:

https://www.medicines.org.uk/emc/product/5300/smpc

DailyMed - CYCLOSPORINE solution [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 23 April 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f3dc2a50-1084-4190-a6f3-37034a04db86

[Internet]. Biocon.com. 2020 [cited 23 April 2020]. Available from:

https://biocon.com/docs/prescribing_information/immunotherapy/psorid_pi.pdf

Search results detail| Kusurino-Shiori(Drug information Sheet) [Internet]. Rad-ar.or.jp. 2020 [cited 23 April 2020]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=32475
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Information on this page was last updated on 12 Jun 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.