Cyclosporine

Description

Cyclosporine is an immuno-suppressant which is used in organ transplant patients, Rheumatoid Arthritis and Psoriasis. It should be used under the supervision of a qualified physician. Close monitoring of kidney function is necessary while receiving this medicine.

Side effects

Major & minor side effects for Cyclosporine

  • Decrease in blood cell count
  • Tremors
  • Headache
  • Nausea and Vomiting
  • Skin rash
  • Fever and chills
  • Abdominal discomfort
  • Facial hair growth
  • Running Nose
  • Muscle cramps

Uses of Cyclosporine

What is it prescribed for?

  • Organ Transplant - Rejection Prophylaxis
  • Rheumatoid Arthritis
  • Psoriasis
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed in 1 to 2 hours.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 10 to 27 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has reported.
  • Usage in pregnancy?
    This medicine is not recommended for pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended in breastfeeding women.

Allergy

Not recommended in patients with known allergy to Cyclosporine.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women.

Breast-feeding

This medicine is not recommended in breastfeeding women.
General warnings

Malignancy

This medicine may increase the risk of lymphoma and other malignancies. Doctors should inform patients about these risks and advise the patient to prevent exposure to sunlight by wearing protective clothes.

Serious infections

The chances of developing infections are higher in the patients receiving this medicine. Hold the treatment and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

Kidney impairment

This medicine is not recommended in the patients with a history of kidney impairment. Close monitoring of kidney function is necessary. The dose should be adjusted based on the creatinine clearance (CrCl).

Liver impairment

This medicine is not recommended in patients with a history of liver impairment. The concentration of this medicine may increase in such patients. The baseline of the liver function tests should be obtained before starting the treatment.

Hyperkalemia

This medicine may increase the levels of potassium in the body and may increase the risk of arrhythmia. Close monitoring of potassium levels is necessary. Medicines that can increase potassium levels like ACE inhibitors and potassium-sparing diuretics should be avoided.

Hypertension

Use with caution in hypertensive patients. Appropriate antihypertensives should be administered to control the blood pressure. Do not use medicine that may increase the potassium levels.

Missed Dose

The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost the time for the next dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amlodipine

Atorvastatin

Nonsteroidal anti-inflammatory drugs

Live attenuated vaccines and related products

Disease interactions

Disease

Information not available.
Food interactions
Consumption of grapefruit juice is not recommended while receiving this medicine. It may increase the Cyclosporine concentration and increase the risk of liver and kidney injury. It is advised to consult the doctor for a proper diet management before receiving this medicine.
Lab interactions
Information not available.
Take Cyclosporine under the supervision of a qualified healthcare professional. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by decreasing the body's immune system activity and helps in preventing body's rejection action of transplanted organs.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Calcineurin inhibitors

Schedule

Schedule H

Cyclosporine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 June 2017]. Available from:

https://www.drugbank.ca/drugs/DB00091

[Internet]. 2017 [cited 12 June 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/33363

DailyMed - Cyclosporine capsule, gelatin coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 12 June 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bfca7088-fe93-abb9-3ec3-e6f5710a69c6

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 5 Jan 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.