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Coversyl-AM 8/5 Tablet
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Coversyl-AM 8/5 Tablet

Manufactured bySERDIA PHARMACEUTICALS (INDIA) PVT. LTD
ContainsAmlodipine (5 mg) + Perindopril (8 mg)
Description
Coversyl-AM 8/5 Tablet is a combination medicine used for the treatment of hypertension (high blood pressure) and stable coronary artery disease. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect. This medicine is not recommended for use in patients less than 18 years of age.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Coversyl-AM 8/5 Tablet

  • Headache
  • Dizziness
  • Vertigo
  • Vomiting
  • Diarrhea
  • Constipation
  • Muscle cramps
  • Ringing or buzzing in the ears
  • Cough
  • Swelling

Uses of Coversyl-AM 8/5 Tablet

What is it prescribed for?

  • Mild to moderate hypertension
  • Stable Coronary Artery Disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is about 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to amlodipine, other calcium-channel blockers, perindopril, any other ACE inhibitors, or any other inactive ingredients present along with these medicines.

Angioedema

This medicine is not recommended for use in patients with a known history of angiotensin converting enzyme inhibitors induced angioedema or hereditary angioedema due to the increased risk of worsening of the patient's condition.

Aliskiren

Coadministration of aliskiren and this medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment (CrCl =< 30 ml/min/1.7 m2) due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypotension

Symptomatic hypotension may occur in patients with volume depletion or patients who are treated with high-dose diuretics. It is advised to correct this condition before initiating treatment with this combination medicine.

Coronary artery disease

This medicine should be used with caution in patients with coronary artery diseases, especially while starting the treatment or increasing the dose, since it may worsen the symptoms of myocardial infarction or angina.

Pediatric use

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Hyperkalemia

This medicine may significantly increase the potassium levels in the blood (hyperkalemia). This may cause serious adverse effects such as fatal cardiac rhythm irregularities. Report any unusual symptoms to the doctor immediately. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Kidney diseases

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver diseases

This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of hepatic failure. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving and Operating machines

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Allopurinol

Carbamazepine

Dexamethasone

Itraconazole

Rifampicin

Aliskiren

Insulin

Diclofenac

Candesartan

Disease interactions

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.

Bone marrow suppression

This medicine should be used with caution in patients with bone marrow suppression due to the increased risk of worsening of the patient's condition. Close monitoring of complete blood count is necessary for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Renal Dysfunction

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
It is recommended to avoid a high potassium diet during treatment with this medicine due to the increased risk of serious adverse effects. Your doctor/dietitian will suggest an appropriate diet for you to avoid a high intake of potassium.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as instructed by your doctor. You are advised to take this medicine before food, preferably in the morning. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlodipine relaxes the heart muscles and the blood vessels. Perindopril relaxes the blood vessels and promotes the smooth flow of blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

ACE inhibitors with calcium channel blocking agents

Schedule

Schedule H
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Information on this page was last updated on 12 May 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.