Home >
Medicine Info >
Coversyl-AM 4/5 Tablet
Loading interface...

Coversyl-AM 4/5 Tablet

Manufactured bySERDIA PHARMACEUTICALS (INDIA) PVT. LTD
ContainsAmlodipine (5 mg) + Perindopril (4 mg)
Description
Coversyl-AM 4/5 Tablet is a combination of Amlodipine and Perindopril. It is used for the treatment of hypertension (high blood pressure) and stable coronary artery disease (a condition where the blood flow to the heart is blocked or restricted). This medicine works by relaxing your blood vessels which eases blood flow easily and controls your blood pressure. This will also reduce the risk of heart attack or a stroke by making it easier for your heart to pump blood throughout your body. Coversyl-AM 4/5 Tablet shows side effects like cough, decreased blood pressure, dizziness, back pain, diarrhoea, vomiting, and swelling in your ankles or feet. These side effects are temporary and will go away with time. Coversyl-AM 4/5 Tablet should be taken before your meal. Take this medicine at the same time every day to avoid any missed dose. Even if you feel better or your blood pressure appears to be under control, do not stop taking it. Abrupt discontinuation may lead to side effects or a sudden increase in your blood pressure. This medicine is safe for long-term use. Coversyl-AM 4/5 Tablet is not recommended for use in children below 18 years of age. Inform your doctor if you have any history of kidney, liver, and heart problems or any other condition. If you are pregnant, this medicine is not recommended as it might harm your unborn foetus, especially if taken during the second and third trimesters.
QUICK LINKS:
Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Coversyl-AM 4/5 Tablet

  • Headache
  • Dizziness
  • Cough
  • Weakness
  • Diarrhoea
  • Stomach pain
  • Back pain
  • Swelling of ankles or feet
  • Vomiting
  • Low blood pressure

Uses of Coversyl-AM 4/5 Tablet

What is it prescribed for?

  • Hypertension
  • Stable Coronary Artery Disease
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Coversyl-AM 4/5 Tablet starts to work in your body in 1-2 hours and reduces high blood pressure. However, to see its full effect, you need to take this medicine for at least a month.
  • How long do the effects of this medicine last?
    The effect of Coversyl-AM 4/5 Tablet lasts for an average duration of approximately 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Coversyl-AM 4/5 Tablet.
  • Can this medicine be taken during pregnancy?
    Coversyl-AM 4/5 Tablet is not recommended for use during pregnancy since it may harm the unborn foetus, especially if taken during the second and third trimesters. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    It is not known if Coversyl-AM 4/5 Tablet passes into the breastmilk. Therefore, consult your doctor if you are breastfeeding before taking this medicine.

Allergy

Avoid taking Coversyl-AM 4/5 Tablet if you are allergic to Amlodipine and/or Perindopril. This could lead to symptoms like redness, swelling, breathing difficulties, hives, etc. You should ask your doctor for another alternative if you have a known history of allergy to this medicine.

Angioedema

Angioedema is an allergic condition in which there is a painless swelling under the skin mostly seen around the face and lips. Coversyl-AM 4/5 Tablet is not recommended for use if you have a history of angioedema, as it may worsen your condition.

Aliskiren

Aliskiren is a medicine used to control blood pressure. Do not use Coversyl-AM 4/5 Tablet if you are taking aliskiren. Concomitant use of these medicines may lead to serious side effects such as low blood pressure and high potassium levels in your blood. The risk is higher if you have a kidney problem or diabetes (high blood sugar level).

Sacubitril

Sacubitril is a medicine used in the treatment of chronic heart failure. It is recommended that you should not take Coversyl-AM 4/5 Tablet within 36 hours before or after taking a medicine that contains sacubitril as it may lead to angioedema (swelling of the face, eye, lips, etc.).
Warnings for special population

Pregnancy

Coversyl-AM 4/5 Tablet is not recommended for use during pregnancy since it may harm the unborn foetus, especially if taken during the second and third trimesters. Consult your doctor if you are pregnant.

Breast-feeding

It is not known if Coversyl-AM 4/5 Tablet passes into the breastmilk. Therefore, consult your doctor if you are breastfeeding before taking this medicine.
General warnings

Hypotension

Hypotension refers to a decrease in blood pressure. Coversyl-AM 4/5 Tablet may cause hypotension, especially when used in combination with other high blood pressure medicines and if you are having low sodium levels in your blood. During therapy with this medication, you should check your blood pressure regularly. Depending on your clinical condition, the doctor may make appropriate dose changes.

Kidney diseases

Coversyl-AM 4/5 Tablet should be used with caution if you have a history of kidney problems. This medicine is excreted via the kidney and may accumulate in your body if there is kidney impairment.

Liver diseases

Coversyl-AM 4/5 Tablet should be used with caution if you have a history of liver problems due to the increased risk of liver failure. Your doctor may suggest tests to regularly monitor your liver functions while you are on this medication. Inform your doctor if you develop any symptoms of jaundice [increased level of bilirubin (blood pigment) in the blood that leads to yellow skin discolouration].

Driving and Operating machines

Coversyl-AM 4/5 Tablet may cause dizziness or weakness and affect your driving ability. Hence, avoid performing any activities that require high mental alertness such as driving or operating machines unless you know how this medicine affects you.

Missed Dose

If you forget to take a dose of Coversyl-AM 4/5 Tablet at a given time, take it as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose of Coversyl-AM 4/5 Tablet. If you suspect that you might have taken an overdose of this medicine, seek immediate medical attention for further guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Allopurinol

Carbamazepine

Dexamethasone

Itraconazole

Rifampicin

Insulin

Diclofenac

Candesartan

Disease interactions

Bone marrow suppression

Bone marrow suppression is a condition in which your bone marrow (a substance found in the bone that produces blood cells) activity is reduced which further leads to a decrease in blood cell count. Take Coversyl-AM 4/5 Tablet with caution in such conditions as this medicine may cause bone marrow suppression. The risk is high if you have kidney impairment.

Congestive heart failure

Congestive heart failure (CHF) is a condition in which your heart is unable to pump blood efficiently. Take Coversyl-AM 4/5 Tablet with caution if you have congestive heart failure as it may cause oliguria (low urine output) and kidney failure. Your doctor may suggest tests to Closely monitor your kidney and heart condition while taking this medicine.

Hemodaialysis

Hemodialysis is a treatment in which a machine is used to filter the waste from the blood when the kidney fails to do so. If you are undergoing hemodialysis, take Coversyl-AM 4/5 Tablet with caution. This medicine may lead to anaphylactoid reactions (life-threatening allergic reactions) in such conditions.

Hyperkalemia

Coversyl-AM 4/5 Tablet may significantly increase the potassium levels in your blood (hyperkalemia). This may cause serious side effects such as irregular heartbeats. Report any unusual symptoms to your doctor immediately. Avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) while taking this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on your clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Coversyl-AM 4/5 Tablet as grapefruit juice can increase the absorption of this medicine in your body. This could lead to excessive lowering of your blood pressure or worsen side effects such as dizziness, headache, swelling of hands and feet, etc.
Avoid a high potassium diet during treatment with Coversyl-AM 4/5 Tablet due to the increased risk of serious side effects. Unless recommended by your doctor, avoid taking salt substitutes or potassium supplements while taking this medicine. Your doctor/dietitian will suggest an appropriate diet to avoid a high intake of potassium.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Coversyl-AM 4/5 Tablet before your meal or as advised by your doctor. Do not take it in a higher dosage than the dose prescribed by your doctor as it can lead to complications. You should not stop taking this medicine abruptly as it can cause withdrawal symptoms. Therefore, it is important to complete the treatment course. If you experience any side effects, consult your doctor immediately. Coversyl-AM 4/5 Tablet may cause dizziness in the first few days, so get up carefully if you've been sitting or lying down. You can also take the medicine before bedtime to avoid dizziness during the day. Coversyl-AM 4/5 Tablet may causes persistent dry cough but it will usually subside after stopping the medicine. This medicine may also raise the potassium level in your blood. Hence, avoid potassium supplements as well as potassium-rich meals like bananas and broccoli.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Coversyl-AM 4/5 Tablet contains Amlodipine and Perindopril that act together to relax blood vessels and control blood pressure. Amlodipine relaxes your heart muscles and blood vessels. Perindopril relaxes the blood vessels and promotes the smooth flow of blood.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

ACE inhibitors with calcium channel blocking agents

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use AMLODIPINE BESYLATE TABLETS safely and effectively. See full prescribing information for AMLODIPINE BESYLATE TABLETS. AMLODIPINE BESYLATE Tablets for oral administration Initial U.S. Approval: 1992. [online] Available at: < [Accessed 14 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1cec7a02-b7a5-49e1-ab64-3a4dab4149d2>

Medicines.org.uk. 2021. Amlodipine 10 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 14 July 2021].

https://www.medicines.org.uk/emc/medicine/24889>

Drugs, H., 2021. Amlodipine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 14 July 2021].

https://medlineplus.gov/druginfo/meds/a692044.html>

Medicines.org.uk. 2021. Perindopril Erbumine 4 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 4 August 2021].

https://www.medicines.org.uk/emc/product/4390/smpc#gref>

Drugs, H., 2021. Perindopril: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 4 August 2021].

https://medlineplus.gov/druginfo/meds/a602017.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - PERINDOPRIL ERBUMINE tablet. [online] Available at: < [Accessed 4 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fcaefca9-e6ca-4c97-9eb8-7f1c619ce4d0>

2021. [online] Available at: < [Accessed 5 August 2021].

https://www.nps.org.au/medicine-finder/apo-perindopril-arginine-amlodipine-5-mg-5-mg-tablets>
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 5 Oct 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.