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Bupron SR 150 Tablet
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Bupron SR 150 Tablet

Manufactured bySUN PHARMA LABORATORIES LTD
ContainsBupropion
Description
Bupron SR 150 Tablet is a prescription medicine containing Bupropion. It is used in the treatment of depression, seasonal affective disorder (depression associated with a change in season, usually during late autumn and winter), and to help in smoking cessation. Bupron SR 150 Tablet works by increasing the levels of chemical messengers in the brain that helps in regulating mood, thus helping to alleviate the symptoms of depression. The mechanism of action in treating smoking addiction is not fully understood. Bupron SR 150 Tablet may cause common side effects like sleep problems, difficulty concentrating, sweating, headache, nausea, vomiting, dry mouth, abdominal pain, anxiety, agitation, tremor, constipation, weight loss, etc. Inform your doctor if these symptoms persist or worsen. Bupron SR 150 Tablet may cause dizziness and sleepiness, so do not drive vehicles or operate heavy machines when taking this medicine. Avoid consuming alcohol during treatment with this medicine as it may increase the risk of side effects. Bupron SR 150 Tablet may be taken with or without food. Take it at the same time each day for ease of remembering. Your doctor will determine the dose and duration of treatment based on your clinical condition. Avoid taking more or less than the recommended dose. Do not stop taking Bupron SR 150 Tablet abruptly, as this may cause a worsening of your symptoms. Inform your doctor about all the medicines you take (especially monoamine oxidase inhibitors like Selegiline, Linezolid, etc.) in order to avoid interaction, which may cause serious side effects. Bupron SR 150 Tablet may not be suitable for everyone. It should be avoided if you have seizures (a condition that causes uncontrolled body movement due to an electrical disturbance in the brain), eating disorders, or if you have recently stopped using sedatives (medications that slow down brain activity and makes you sleepy). Inform your doctor if you have or have had head injuries, high blood pressure, angle-closure glaucoma (an eye condition that develops when the structure inside the eye that allows the draining of the fluid from the eye gets blocked, causing an increase in fluid pressure inside the eyes), or liver, kidney, or heart problems before starting the treatment with this medicine. Bupron SR 150 Tablet is not recommended for use in children below 18 years of age due to the lack of safety and efficacy data. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding before taking this medicine.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Bupron SR 150 Tablet

  • Anxiety
  • Irritability
  • Restlessness
  • Irregular heartbeat
  • Trouble sleeping
  • Headache
  • Ringing or buzzing in the ears
  • Confusion
  • Dry mouth
  • Nausea or vomiting
  • Dizziness
  • Drowsiness
  • Constipation

Uses of Bupron SR 150 Tablet

What is it prescribed for?

  • Major depressive disorder
  • Smoking cessation
  • Seasonal Affective Disorder
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Bupron SR 150 Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Bupron SR 150 Tablet remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this Bupron SR 150 Tablet due to the increased risk of side effects such as seizures, dizziness, mood and behavioural changes, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Bupron SR 150 Tablet.
  • Can this medicine be taken during pregnancy?
    Bupron SR 150 Tablet is not recommended for use in pregnancy unless necessary. The risks and benefits should be discussed with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Bupron SR 150 Tablet may pass into breastmilk. Hence it is not recommended for use while breastfeeding.

Allergy

Avoid taking Bupron SR 150 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Monoamine oxidase inhibitors (MAOI)

Monoamine oxidase inhibitors (MAOIs) are medications that are used to treat depression. Bupron SR 150 Tablet should be avoided if you are taking MAOIs due to the increased risk of serious and life-threatening side effects. Avoid taking this medicine for at least 14 days after the discontinuation of MAOIs.

Anorexia nervosa and Bulimia

Bupron SR 150 Tablet is not recommended for use if you have or have had eating disorders such as anorexia nervosa (a serious psychological condition characterised by extreme restriction of calorie intake due to intense fear of weight gain) or bulimia (an eating disorder where a person binges on food and then follows extreme methods to get rid of it to avoid weight gain). This medicine may cause seizures in such cases.

Epilepsy (Seizures)

Seizure is a central nervous system condition in which abnormal electrical signals in the brain are generated, resulting in involuntary movements and loss of consciousness. Bupron SR 150 Tablet is not recommended for use if you have seizures as it may further trigger a seizure attack and worsen your condition. It should be avoided if you use sedatives (medicines that slow down the brain activity and makes you sleepy) and you stop using them abruptly, due to the increased risk of seizures.
Warnings for special population

Pregnancy

Bupron SR 150 Tablet is not recommended for use in pregnancy unless necessary. The risks and benefits should be discussed with your doctor before taking this medicine.

Breast-feeding

Bupron SR 150 Tablet may pass into breastmilk. Hence it is not recommended for use while breastfeeding.
General warnings

Kidney impairment

Bupron SR 150 Tablet should be used with caution if you have impaired kidney function due to the increased risk of side effects. Your doctor may recommend dose adjustments based on your clinical condition.

Weight change

Bupron SR 150 Tablet should be used with caution as it may cause weight change. Consult your doctor if you have any concerns.

Driving vehicles or operating machines

Bupron SR 150 Tablet may cause dizziness, confusion, drowsiness, etc. Hence avoid performing activities that require mental focus, such as driving vehicles or operating machines, if you experience such symptoms during treatment with this medicine.

Use in children

Bupron SR 150 Tablet is not recommended for use in children less than 18 years of age as the safety and efficacy data are not clinically established.

Suicidal tendencies

Bupron SR 150 Tablet should be used with caution due to the increased risk of worsening of depression and suicidal tendencies. This risk is especially higher during the initiation of treatment and at the time of dose modification. Hence closely monitoring for any change in mood or behaviour. Consult your doctor immediately if you develop suicidal thoughts.

Hypertension

Bupron SR 150 Tablet may increase the blood pressure levels. Therefore it should be used with caution if you have hypertension (high blood pressure) as it may further worsen your condition. Monitor your blood pressure regularly while you are taking this medicine.

Seizure disorder

Bupron SR 150 Tablet should be used with extreme caution if you have conditions that may increase the risk of seizures such as severe head injury, CNS tumour, CNS infection, brain damage, excessive use of or abrupt withdrawal of alcohol, etc., due to the increased risk of worsening of the condition. Consult your doctor before taking this medicine.

Missed Dose

Take the missed dose of Bupron SR 150 Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Contact your doctor in case of an overdose of Bupron SR 150 Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this Bupron SR 150 Tablet due to the increased risk of side effects such as seizures, dizziness, mood and behavioural changes, etc.
Interaction with Medicine

Deflazacort

Levodopa

Amantadine

Codeine

Aripiprazole

Phenytoin

Carbamazepine

Disease interactions

Liver Disease

Bupron SR 150 Tablet should be used with caution if you have liver problems as it may cause an accumulation of this medicine in the body, thus increasing the risk of side effects. Your doctor may recommend appropriate dose adjustments based on your clinical condition.

Angle Closure Glaucoma

Angle-closure glaucoma is a condition that develops when the drainage angle (a structure inside the eye that allows the draining of the fluid from the eye) gets blocked. This may cause an increase in fluid pressure inside the eyes and lead to vision loss. Bupron SR 150 Tablet should be used with caution if you have angle-closure glaucoma as this medicine may cause an increase in fluid pressure within the eyes and further worsen your condition.

Psychosis

Bupron SR 150 Tablet should be used with caution as it may cause confusion, hallucinations, psychosis (a mental health condition characterised by loss of contact with reality), etc. Consult your doctor if you have any concerns.

Bipolar disorder

Bupron SR 150 Tablet may cause activation of mania or hypomania. Hence it should be used with caution if you have a family history of mania (abnormally elevated mood and hyperactivity), hypomania (less serve form of mania with energy levels higher than usual), or bipolar disorder (extreme mood changes with emotional highs and lows).
Food interactions
Information not available.
Lab interactions

Urine test for Amphetamines

Report the use of Bupron SR 150 Tablet to the doctor before undergoing a urine test for the screening of Amphetamines (central nervous system stimulant medicine). A false-positive result may be obtained if this test is performed while taking this medicine.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Bupron SR 150 Tablet with or without food. Do not break, chew, or crush the tablet. Swallow as a whole with plenty of water. Do not take larger or smaller amounts than prescribed as it may cause altered effects of this medicine or increased risk of side effects. Consult your doctor if you experience side effects that persist or worsen. The use of Bupron SR 150 Tablet may cause weight changes. Consult your doctor if you have any concerns Avoid taking this medicine if you have seizures (fits) or other conditions that may cause seizures. The use of this medicine may further worsen your condition. Consult your doctor if you experience worsening of depression or develop suicidal thoughts, especially at the beginning of the treatment or during dose change.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Bupron SR 150 Tablet works by increasing the levels of chemical messengers like dopamine, norepinephrine, and serotonin in the brain. This helps in counteracting mood depressive disorders and other psychological conditions. The mechanism underlying its use in smoking addiction is not clinically understood.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Miscellaneous antidepressants, Smoking cessation agents

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. PubChem. [online] Available at: < [Accessed 17 November 2021].

https://pubchem.ncbi.nlm.nih.gov/#query=BUPROPION>

Drugs, H., 2021. Bupropion: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 17 November 2021].

https://medlineplus.gov/druginfo/meds/a695033.html

Medicines.org.uk. 2021. Zyban 150 mg prolonged release tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 17 November 2021].

https://www.medicines.org.uk/emc/product/3827/smpc#

Dailymed.nlm.nih.gov. 2021. DailyMed - BUPROPION HYDROCHLORIDE (SR)- bupropion hydrochloride tablet, extended release. [online] Available at: [Accessed 17 November 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9d2c209b-248e-4e26-9cde-fe0abe4428c1

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 4 August 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/20358s19lbl.pdf
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Information on this page was last updated on 4 Aug 2022

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