Bupropion
Description
Bupropion is used in the treatment of depression, smoking cessation, and seasonal affective disorder. This medicine is not recommended for use in patients less than 18 years of age.
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Side effects
Major & minor side effects for Bupropion
- Anxiety
- Irritability
- Restlessness
- Irregular heartbeat
- Trouble sleeping
- Headache
- Skin Rash
- Ringing or buzzing in the ears
- Confusion
Uses of Bupropion
What is it prescribed for?
- Major depressive disorder
- Seasonal Affective Disorder
- Smoking cessation
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as seizures, dizziness, mood and behavioral changes, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
- Is it habit forming?No habit-forming tendencies were reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition
Allergy
This medicine is not recommended for use in patients with a known allergy to bupropion or any other inactive ingredients present along with it.
Monoamine oxidase inhibitors (MAOI)
This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between the administration of these medicines.
Anorexia nervosa and Bulimia
This medicine is not recommended for use in patients with a current or history of eating disorders such as anorexia nervosa or bulimia due to the risk of worsening of the patient's condition.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition
General warnings
Liver impairment
This medicine should be used with caution in patients with an impaired liver function due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Kidney impairment
This medicine should be used with caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Weight Loss
Usage of this medicine may increase the risk of weight loss which may be undesirable in patients suffering from anorexia, malnutrition, excessive weight loss, etc. Regular monitoring of weight change is necessary while receiving this medicine.
Driving or Operating machinery
Use of this medicine may cause dizziness, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Use in children
This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
Suicidal tendencies
This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young patients. Patients should be closely monitored for any change in mood or behavior. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Hypertension
This medicine may increase the blood pressure levels and therefore should be used with caution in patients with hypertension (high blood pressure) due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Seizure disorder
This medicine should be used with extreme caution in patients with seizure disorder or conditions that may increase the risk of seizures such as severe head injury, CNS tumor, CNS infection, severe stroke, etc. due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.
Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as seizures, dizziness, mood and behavioral changes, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine
Deflazacort
Amoxapine
Doxepin
Amantadine
Codeine
Aripiprazole
Disease interactions
Liver Disease
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Seizure disorders
This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Angle Closure Glaucoma
This medicine should be used with caution in patients with angle-closure glaucoma since it may increase the risk of a rise in intraocular pressure. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Psychosis
This medicine should be used with caution in patients with psychotic disorders since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Urine test for Amphetamines
Report the use of this medicine to the doctor if you are undergoing this test. A false positive result may be obtained if this test is performed while taking this medicine. Do not stop the use of any medicine without consulting your doctor.
Take this medicine with or without food. Do not take larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
It works by increasing certain chemical substances in the brain which helps in maintaining the mental balance.
Legal Status
Classification
Category
Miscellaneous antidepressants, Smoking cessation agents
Schedule
Schedule H
Bupropion - DrugBank [Internet]. Drugbank.ca. 2018 [cited 14 September 2018]. Available from:
[Internet]. Gsksource.com. 2018 [cited 14 September 2018]. Available from:
Bupropion: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 14 September 2018]. Available from:
Zyban 150 mg prolonged release tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 14 September 2018]. Available from:
Information on this page was last updated on 27 Mar 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.