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Restasis 0.05 % Injection
Manufactured byAllergan India Ltd.
ContainsCyclosporine
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Description
Restasis 0.05 % Injection is an immuno-suppressant which is used in kidney, liver, and heart transplant patients to prevent organ rejection. Close monitoring of kidney function is necessary while receiving this medicine.
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Substitutes
List of substitutes for Restasis 0.05 % Injection
Side effects
Major & minor side effects for Restasis 0.05 % Injection
Decrease in blood cell count
Tremors
Headache
Nausea and Vomiting
Skin rash
Fever and chills
Abdominal discomfort
Facial hair growth
Running Nose
Uses of Restasis 0.05 % Injection
What is it prescribed for?
Organ Transplant - Rejection Prophylaxis
This medicine is used to reduce the immune response of the body in organ (kidney, liver, and heart) transplant patients.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for this medicine to show its action is not clinically established.How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit forming tendencies has been reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. If the medicine is used, close monitoring of the infant for any undesired effects is necessary.
Allergy
This medicine is not recommended for use in patients with a known history of allergy to cyclosporine, cyclosporin, or any other inactive ingredients present in the formulation.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. If the medicine is used, close monitoring of the infant for any undesired effects is necessary.
General warnings
Malignancies
This medicine may increase the risk of developing lymphoma and other malignancies in some patients, especially of the skin. Doctors should inform patients about these risks and advise the patient to prevent exposure to the sunlight by wearing protective clothing.
Serious infections
This medicine should be used with caution in patients who are at risk of developing serious infections since it suppresses the immune system and further increases the risk of infections. Any symptoms such as a sore throat, fever, chills, etc. should be reported to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Kidney impairment
This medicine is not recommended in patients with a history of kidney impairment. Close monitoring of kidney function is necessary. The dose should be adjusted based on the creatinine clearance (CrCl).
Hyperkalemia
This medicine may increase the levels of potassium in the body and may increase the risk of arrhythmia. Close monitoring of potassium levels is necessary while receiving this medicine. Medicines that can increase the potassium levels like ACE inhibitors and potassium-sparing diuretics should be avoided. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Hypertension
This medicine should be used with extreme caution in patients suffering from elevated blood pressure due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Other uses
Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.
Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Amlodipine
Live attenuated vaccines and related products
Citalopram
Gefitinib
Ibuprofen
Diclofenac
Disease interactions
Kidney Disease
This medicine is not recommended for use in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended while receiving this medicine as it may increase this medicine's concentration and increase the risk of liver and kidney injury. It is advised to consult the doctor for a proper diet management before receiving this medicine.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor and do not miss an appointment to receive this medicine. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous
How it works
This medicine works by decreasing the body's immune system activity and helps in preventing the body's rejection action of transplanted organs.
Legal Status
Classification
Category
Calcineurin inhibitors
Schedule
Schedule H
Cyclosporine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 June 2017]. Available from:
SANDIMMUN Concentrate for Solution for Infusion 50mg/ml - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 23 April 2020]. Available from:
DailyMed - CYCLOSPORINE injection, solution [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 23 April 2020]. Available from:
Search results detail| Kusurino-Shiori(Drug information Sheet) [Internet]. Rad-ar.or.jp. 2020 [cited 23 April 2020]. Available from:
Cyclosporine Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 23 April 2020]. Available from:
Related Questions
Question:
Can. We use restasis eye drops for chronic dry eyes.Now I am using systane eye drops for dry eyes.ve...more
Answer from Dr. A Raja Prasanna Kumar
You can use them.systane also ok.pl use frequently and reduce screen time. Pl co...more
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I have dry eye and visit doctor regularly when I have symptom, but haven't done any related test. Sh...more
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You should not start with cyclosporine eye drops for dryness ,you may use Refres...more
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Answer from Dr. Vaibhev Mittal
Hello
U can use restasis
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Information on this page was last updated on 12 Jun 2020
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.