SPECIMEN NO.: S/276/23
NATURE OF SPECIMEN: Tissue from Right cheek.
CLINCIAL HISTORY: ? Ca cheek. Leukoplakia pattern bilateral cheek with submucosal fibrosis.
GROSS EXAMINATION: Received single grey brown soft tissue piece measures 0.8x0.4x0.3 cm.
MICROSECTION NO.: MS/769/23
MICROSCOPY: Section reveals atypical squamous cells arranged in groups, nests and as single
infiltrating cells in the fibrocollagenous stroma and showing infiltration into the muscle tissue
included. These atypical cells are lining the overlying squamous epithelium which shows breeched
basement membrane and intraepithelial lymphocytes as well as epithelial denudation. These
atypical cells have round to oval nuclei, coarse chromatin, conspicuous nucleoli and moderate
cytoplasm. Mitosis and individual cell keratinization noted. The surrounded stroma reveals
moderate mononuclear infiltrate.
IMPRESSION: Moderately differentiated squamous cell carcinoma, Right cheek.
ADVISED: Clinical correlatio
Answers (3)
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58 y male cheek biopsy showing moderately differentiated squamous cell carcinoma. Now we have to do staging workup to decide the treatment. If it's in early stage surgery is the preferred choice. If locally advanced chemo with radiotherapy is the choice. If advanced or metastatic then ohemo with or without immunotherapy is the choice. First you please get a ct scan neck and chest or pet ct
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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