Need suggestion in diagnosing disease.

Hi, Last 6 months back i was having heart pain and taken urea breath test and +ve for h pylori. My gastro recommended strong antibiotics like daily 3000mg for 10 days. After the mediciations the result was -ve for h pylori but my calprotectin test results are 360. Doctor recommended to continue PPI for 1 more month and calprotectin test after a month. This time my i still have acid reflux and undergone barium test and the results was GERD along with that my calprotectin levels raised to more than 1000. I have under probotics and PPI. Doctor scheduled colonoscopy for next week. What is the main reason for increased calprotectin? PPI or any other infections will elevate calprotectin? A part from acid reflux i dont have any pains in stomach or bloody stools