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Lipid profile and hscrp
26-year-old female, gym-goer since 2018 with a weightlifting coach. Breathlessness on brisk walking, and occasional irregular periods. Mother has arthritis and diabetes. No family history of early heart disease. Took one emergency contraceptive pill 2 months ago.
Reports (11 Oct 2026):
Thyroid: TSH 4.24 (high), T4 4.52 (low), T3 72.8 (low)
Lipids: total cholesterol 235,
LDL 134.7,
non-HDL 193,
triglycerides 292,
HDL 41.9,
ApoB 129,
ApoA1 137
hs-CRP 3.69 (high), ESR 10 (normal)
Sodium 133.9 (low), B12 919 (high), lymphocytes 46% (high)
Normal: HbA1c 5.2%
fasting glucose 97,
haemoglobin 12.8
Answers (2)
You have mixed dyslipidemia, characterized by elevated total cholesterol (235 mg/dL), LDL cholesterol (134.7 mg/dL), triglycerides (292 mg/dL), non-HDL cholesterol (193 mg/dL) and ApoB (129 mg/dL). hs-CRP is elevated at 3.69 mg/L. Thyroid profile shows normal TSH with low T4 and T3. HbA1c and fasting glucose are within the normal range. Breathlessness on brisk walking and irregular menstrual cycles warrant further clinical evaluation.
Next Steps
Follow a heart-healthy diet (DASH), reduction of refined carbohydrates and added sugars, avoidance of alcohol, and regular aerobic exercise alongside resistance training.
Consider evaluation for polycystic ovary syndrome (PCOS) or other causes of menstrual irregularity, guided by history and examination.
Reassess lipid levels 3 months after lifestyle modifications to assess for need of Pharmacotherapy .
Health Tips
Triglycerides of 292 mg/dL are moderately elevated and warrant lifestyle modification
restrict refined sugars, fried food intake
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Dr. Ankita Gahlot
Obstetrician
12 yrs exp
Bangalore
A high TSH together with low T4 and T3 is a hypothyroid pattern. This commonly raises cholesterol, triglycerides and hs-CRP the way yours are, and it also fits with your breathlessness and irregular periods. The high B12 and lymphocytes matter far less here.
Next Steps
This needs a repeat thyroid panel and a thyroid antibody test to confirm it. Starting thyroid treatment under a doctor's guidance usually brings the lipid and hs-CRP numbers down over a few months too.
Health Tips
Please see an endocrinologist or physician soon for this. See a gynaecologist as well if your periods stay irregular once your thyroid is treated.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.