Jak2(v617F)mutation-PCR positive in repo

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Asked for Female, 54 Years

I am having history of high platelet upto 6 lakh so doctor recommended to take bone marrow biopsy it shows -Reactive and suggest for mpn test.. Calreticulin mutation-not detected Jak2(v617F)mutation-PCR positive Mpl mutation - not detected BCR/ABL Qual - not detected What does jak2 mutation positive means??

Answers (1)

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Dr. Savio James Radiation Oncologist 8 yrs exp Cochin · Accepted Answer

Dr. Savio James

Radiation Oncologist 8 yrs exp Cochin

A JAK2 mutation is like a little small mutation in your genes that can cause your body to make too many blood cells, including platelets. This can sometimes be a sign of conditions like polycythemia vera or essential thrombocythemia. Are you presently having any complaints ? Or was this done since your blood showed increased platelets? Is your blood picture otherwise okay?

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