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Hospitalised for Extreme Abdominal Pain
I was recently hospitalised because i arrived in emergency with extreme abdominal pain. They did both USG and Endoscopy and both report came out totally normal. Some things were abnormal in my LFT (attached the file). writing some of the the haematology abnormalities here since i can't attach the file. The ESR 1st Hr is high-normal at 42 mm/1st hr (reference 36 - 46 mm/1st hr) My white blood cell differential shows an immune response pattern: Neutrophils are significantly elevated at 82% (reference 45 - 75%), and Lymphocytes are decreased at 12% (reference 25 - 45%). The Total WBC count is at the high end of normal, at 10920 /cumm (reference 4000 - 11000 /cumm). What is the underlying diagnosis for the combination of: chronic acid reflux,vomiting,extreme abdominal pain, significantly high inflammatory markers (CRP/Neutrophils), and highly deranged liver enzymes (AST/GGT), especially when the USG and Endoscopy were completely NORMAL?
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Severe pain in upper abdomen has many causes: the combination of deranged Liver enzymes and raised CRP can be seen in Pancreatitis, although you don’t have Gall stones: further steps to determine the possible diagnosis would be 1. Pancreatitis tests Se Amylase and lipase 2. CT Scan abdomen with IV contrast Further management as per reports If all reports are normal then conservative treatment 3. Acid reflux is a different problem and will need its own investigations like Manometey and 24 hour pH
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Your reports and symptoms suggest a transient inflammatory or hepatocellular reaction, likely secondary to acute gastritis, viral infection, or drug-induced hepatic stress, rather than a structural liver or gastric disease. Interpretation of findings: • Liver enzymes: AST (115 U/L), ALT (79 U/L), and GGT (108 U/L) are mildly to moderately elevated → indicating a hepatocellular or mixed pattern of liver irritation. Bilirubin, albumin, and alkaline phosphatase are normal → liver function is preserved. • Inflammatory markers: CRP (9 mg/L) and neutrophilia (82%) with relative lymphopenia indicate an acute inflammatory or infective response. ESR (42 mm/hr) further supports the same. • Pancreatic enzymes (amylase/lipase) are normal → pancreatitis is excluded. • USG and endoscopy being normal rule out structural or ulcerative lesions. This overall pattern fits with a reactive or viral hepatitis picture, or sometimes post-infectious gastritis with transient hepatic inflammation, rather than a chronic or serious pathology.
Next Steps
1. A thorough clinical examination to localize the exact site and character of abdominal pain (upper, mid, right, or diffuse) can help narrow the diagnosis — for example, differentiating between hepatobiliary, gastric, or colonic causes. 2. Repeat LFT in 2–3 weeks — transient enzyme elevation often resolves once inflammation subsides. 3. Avoid hepatotoxic medications or supplements, including unnecessary paracetamol, herbal, or over-the-counter tonics. 4. Maintain a light, non-spicy diet and adequate hydration. 5. If LFT remains abnormal, further evaluation with: • Viral hepatitis panel (HAV, HBV, HCV, EBV) • Autoimmune markers (ANA, ASMA) • Repeat abdominal ultrasound focusing on liver texture.
Health Tips
Liver enzyme elevations of this degree are common after viral or inflammatory illnesses and typically resolve with rest, hydration, and avoidance of hepatotoxic agents. A focused clinical re-examination often reveals subtle findings that guide further targeted tests and prevent unnecessary worry.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.