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Hormonal Imbalance 2
So I've been on Testosterone Undecanoate 40mg twice daily for a 20 days now and repeated blood tests and Free Testosterone has fallen from 11.7 to 10.7 ng/dl.
Also my Iron - 69ug/dl,
Vit D 25Hydroxy - 19.52ng/ml,
B12 - 168pg/ml,
T3 total - 0.82ng/ml,
Progesterone - 0.26 ng/ml,
are down
Total cholesterol - 277 mg/dl,
LDL - 169.6 mg/dl
are high.
I don't know what to do now.
I'm taking Finasteride, Biotin for alopecia, Fluoxetine for OCD and currently on Serratiopeptidase, Aceclofenac & Paracetamol, Cefixime & Lactic acid, Montelukast & Levocetrizine for inflamed tonsils and blocked ear.
Answers (13)
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Difficult to know if your health will change ie improve from the medications you are taking.
The medium and long term effects of some of the medications you are taking is concerning.
You will benefit from speaking to a clinical psychologist.
All the best.
J G S R (online) clinic
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Your reports show low Vitamin D, B12, T3, progesterone and iron levels, along with high LDL and total cholesterol. These deficiencies and lipid abnormalities can themselves affect energy levels, mood, metabolism and even hormonal balance.
Testosterone levels may fluctuate in the initial weeks of TRT; falling free testosterone despite supplementation can happen if dosage, frequency, absorption, or SHBG levels are not aligned. Finasteride, fluoxetine and weight can also influence hormone balance.
At this stage, you need a structured approach rather than adding or stopping medicines on your own. I would recommend:
1. Re-evaluation by an endocrinologist to adjust your TRT dose and check SHBG, LH/FSH, estradiol.
2. Correct vitamin D, B12 and iron deficiencies with appropriate supplements.
3. Address high cholesterol with diet changes, exercise and medical therapy if required.
4. Review all medications (especially finasteride and fluoxetine) with your treating doctor to ensure there is no interaction affecting hormones.
Hormonal therapy must be individualized — please avoid changing doses without supervision. With proper correction of deficiencies and medical guidance, your levels can stabilize.
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Consult
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Abnormal reports
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Consult superspecialist like endocrinologist
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If you want to discuss your problem in more detail, feel free to message me on WhatsApp at nine one one nine two five five six nine nine for a free detailed discussion
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Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Dr. Gaurav Jaiswal
General Physician
6 yrs exp
Jhansi
Avoid fried and spicy food
Water intake more
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Dr. Shahbaz Khan
General Physician
4 yrs exp
Delhi
Needs detailed history and evaluation consider consultation with a endocrinologist
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Dr. Chaithra H
General Physician
5 yrs exp
Bangalore
Diabetic diet
Avoid oily and junk foods
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Dr. Shaikh Huzaif
General Physician
18 yrs exp
Aurangabad
Please consult
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Dr. Abhishek Anand
General Physician
3 yrs exp
Kolkata
Your repeat blood test results show multiple factors that are all connected, and importantly, none of them suggest any dangerous condition -they mainly indicate that your body is under stress from illness, medications, and low vitamin levels.
First, regarding testosterone levels:
You have been taking oral Testosterone Undecanoate for only 20 days. This form of testosterone is absorbed through the intestine and can fluctuate depending on food intake, gut absorption, and concurrent medications. Finasteride, fluoxetine, ongoing infection, poor sleep, and low vitamin D/B12 can all temporarily suppress testosterone activity. A mild fall from 11.7 to 10.7 ng/dL is not concerning and often stabilizes over 6–8 weeks. The dose may need adjustment later, but this is not a treatment failure.
Your vitamin D (19.5), B12 (168), and iron (69) levels are low. These deficiencies commonly cause fatigue, low mood, muscle weakness, and even affect testosterone metabolism. Correcting these alone often improves overall hormonal balance.
Your temporary infection (inflamed tonsils and blocked ear), along with the antibiotics and anti-inflammatory medicines you are currently taking, can also affect appetite, vitamin absorption, and stress hormones.
The high LDL and total cholesterol can occur due to genetics, low activity during illness, stress, and even low thyroid or low vitamin D levels. Once your infection settles, and vitamin levels improve, these often come down.
Next Steps
1. Continue your current testosterone dose. Re-evaluate levels after 6–8 weeks, not now, because early fluctuations are normal.
2.Start correcting vitamin deficiencies, as they directly affect hormone response:
Vitamin D3: 60,000 IU once weekly for 8 weeks
Vitamin B12: 1500 mcg daily or weekly injections if needed
Iron supplement after food (if no gastritis)
3.Manage cholesterol with diet for 6 weeks; medication is needed only if levels stay high afterward.
4.Continue your current treatment for the throat and ear inflammation - these conditions can temporarily disturb hormone and vitamin absorption.
5.Do not worry about finasteride or fluoxetine-they can slightly affect sexual hormones but do not cause dangerous drops.
6.Repeat a complete panel after you have recovered from the infection:
Free and total testosterone
LH, FSH
Vitamin D, B12, iron studies
Thyroid profile
Lipid profile
Health Tips
Right now, the most important thing is to treat the ongoing infection, correct vitamin deficiencies, and let your body stabilize.
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Dr. Vetsa Sri Krishna Chaitanya
General Physician
6 yrs exp
Rajahmundry
Need few more details please consult for further evaluation
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