HIV Test Index Value. To worry or not?

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HIV index value is a measure of the amount of antibodies against the human immunodeficiency virus (HIV) in a person's blood sample. It is calculated by dividing the optical density (OD) of the sample by the OD of the cut-off value, which is a reference point that determines whether the test result is positive or negative. The cut-off value is usually set at more than 1, meaning that any test with the value more than 1 is positive . Iindex val could also be positive due to other factors, such as cross-reactivity with other antibodies, technical errors, or recent exposure to HIV that has not yet triggered a sufficient immune response. Therefore, it is important to understand that the HIV index value is not a definitive diagnosis of HIV infection, but rather a screening tool that helps to identify people who may need further testing and counseling. As CMIA and CLIA are different methods, values may differ. Hence no need to worry.

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