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H pylery infection
What is resistance second line means please clear it properly as i have already completed 14 days course and already tested h pylery stool antigen test which is negetive and have passed one and half years but still occasionally problem arises at present my almost all blood test reports are normal so advise me what to do in this circumstances
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Since your stool antigen test is negative, H. pylori is fully eradicated â no second line treatment needed. Ongoing occasional symptoms after 1.5 years are likely functional dyspepsia or post-infectious IBS. Take a PPI like pantoprazole for 4 weeks, add probiotics, avoid spicy/oily food and stress. No more antibiotics needed.
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Consult me on Practo if symptoms persist for further management.
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Second-line treatment” means a different combination of antibiotics and acid-suppressing medication used only if the first H. pylori treatment fails or the infection is still present. Since you completed a 14-day course and your stool antigen test is negative, H. pylori has most likely been eradicated. Occasional symptoms after eradication are common and may be due to gastritis, acid reflux, functional dyspepsia, or another gastrointestinal condition rather than persistent H. pylori. If symptoms continue or worsen, consult a gastroenterologist for evaluation. An upper GI endoscopy may be considered, especially at your age or if you have weight loss, anemia, vomiting, difficulty swallowing, or bleeding. Avoid self-medicating with antibiotics unless repeat testing confirms reinfection.
Next Steps
1. Completed a 14-day H. pylori treatment course.
2. Had a stool antigen test, which came back negative (suggesting the infection was eradicated).
3. Waited about 1.5 years since completing treatment.
4. Had blood tests, which are reported as normal.
5. Still experiences occasional symptoms and is asking what to do next.
Health Tips
Visit a gastroenterologist for reassessment.
* If symptoms persist, an upper GI endoscopy may be recommended, especially because the patient is 63 years old and has a low body weight (44 kg).
* Consider evaluation for acid reflux, gastritis, functional dyspepsia, or other gastrointestinal conditions, since the H. pylori test is negative.
* Avoid taking another course of H. pylori antibiotics unless repeat testing confirms a recurrent infection.
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Repeat ugie with rut
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Mr. Jitender koli
Gastroenterologist
16 yrs exp
Delhi
A negative H. pylori stool antigen test after completing a full 14-day treatment generally means that the infection has been successfully eradicated, provided the test was done at least 4 weeks after antibiotics and at least 2 weeks after stopping proton pump inhibitors (PPIs).
Regarding your question about "second-line resistance":
Resistance means the H. pylori bacteria are not killed by one or more antibiotics because they have developed the ability to survive those medications.
Second-line treatment is only needed if the first treatment fails and the infection is still present on repeat testing.
If the stool antigen test is negative, there is no evidence that H. pylori is still present, so antibiotic resistance is not a likely explanation for your current symptoms.
Why are you still having occasional symptoms?
Even after H. pylori has been eradicated, some people continue to experience symptoms due to reasons such as:
Functional dyspepsia (sensitive stomach without an ongoing infection)
Acid reflux (GERD)
Gastritis that takes time to heal
Dietary triggers (spicy, oily, acidic foods, caffeine, alcohol)
Stress or anxiety, which can worsen stomach symptoms
Less commonly, other gastrointestinal conditions that need evaluation
Since your:
â H. pylori stool antigen is negative,
â 14-day treatment was completed,
â Blood tests are normal,
â Symptoms are only occasional after 1½ years,
repeating H. pylori antibiotics is not recommended unless testing becomes positive again or your doctor has another reason to suspect reinfection.
What should you do now?
Consult a gastroenterologist if symptoms persist or become more frequent.
Maintain regular meal timings and avoid foods that trigger your symptoms.
If symptoms are suggestive of acidity, your doctor may recommend a short course of a PPI or another acid-suppressing medication.
If you develop any alarm symptomsâsuch as weight loss, difficulty swallowing, persistent vomiting, black stools, vomiting blood, or anemiaâyou should undergo an upper GI endoscopy promptly.
If symptoms are recurrent despite treatment, your gastroenterologist may consider an upper GI endoscopy to look for gastritis, ulcers, reflux disease, or other causes.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.