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Antibiotics and adalumimab
Can we take antibiotics for bacterial infection like clarithromycin , metronidazole while on biologics therapy like adalumimab 40 ( exemptia 40 mg) once in 10 days ..does antibiotics reduce the effectiveness of the biologic
Answers (3)
Yes, clarithromycin and Metrogyl (metronidazole) can generally be taken for a bacterial infection while you are on adalimumab (40 mg). There is no major direct interaction between these medicines. However, since adalimumab can lower immunity, the infection should be monitored closely. If the infection is severe, associated with fever or significant weakness, the next adalimumab dose may need to be postponed until the infection has settled.
Next Steps
If the infection is mild and has completely resolved by the next dose in about 10 days, adalimumab can usually be continued after confirmation with your treating doctor.
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As per books no interaction with the above antibiotics. Yes adalimumab decreases immunity so infection chances increase and also the severity of infection.
Next Steps
What is the indication of adalimumab in your situation. What kind of bacterial infection you have.
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Visit your primary doctor or nearby center.
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Dr. Arun Prakash
Bariatric Surgeon
11 yrs exp
Bhavnagar
Yes, antibiotics such as clarithromycin and metronidazole can generally be taken while receiving adalimumab (Exemptia 40 mg), provided they are prescribed for a confirmed or suspected bacterial infection.
These antibiotics do not normally reduce the effectiveness of adalimumab, and there are no major direct drug interactions generally expected between them.
However, adalimumab suppresses certain immune responses and may increase your susceptibility to infections.
The important concern is the severity of the infection, rather than the antibiotics themselves.
If you have a serious or active significant infection, your treating specialist may advise temporarily withholding adalimumab until the infection is controlled. Do not stop or change the injection schedule without medical advice.
For a mild infection, treatment may sometimes be continued after assessment.
Please let me know why you are receiving adalimumab and which bacterial infection you are being treated for, so I can guide you more specifically.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.