Sudden darkening of knuckles can be caused by several factors. High cortisol or
B12 deficiency usually cause gradual, not sudden, pigmentation changes. Sudden darkening may suggest other causes like post-inflammatory changes or acanthosis nigricans.
A proper evaluation with blood tests and skin examination is important. An online consult will help identify the cause and guide treatment.
𩺠â Dr. Silky Priya
Consultant Dermatologist, Silky Skin Solutions, Pune
Available for online consults via Practo