Firstly it is difficult to understand the case since you havent mentioned the symptoms but just the name of two conditions.. Othello syndrome and mania both of which are very different from each other. Secondly, psychiatric conditions take time to respond and arent so quick to resolve in the first place. we will need to be patient with our approach and wait for results. Detailed history will be needed before i can say anything with specificity and certainty.

Othello syndrome - Delusional disorder and mania- Bipolar spectrum disorder are distinct psychiatric conditions. Othello syndrome, also known as delusional jealousy, is characterized by an intense, unfounded belief that a partner is unfaithful, leading to obsessive thoughts, compulsive checking, and aggressive or controlling behaviors. Common causes is neurotransmitter dysregulation leading to psychosis, substance use particularly alcoholism can be a trigger, genetics- strong family history of psychiatric disorders, neurological conditions; but cause is difficult to identify in majority of the cases. Mania, on the other hand, is a mood state seen in bipolar disorder, characterized by elevated or irritable mood, hyperactivity, impulsivity, and sometimes delusions of grandeur or paranoia, heightened self esteem, reduced sleep, increased goal directed activity/increased psychomotor activity, loss of judgment. While Othello syndrome focuses exclusively on delusions of infidelity, mania involves a broader spectrum of mood and behavioral dysregulation. A person suffering from mania can have various delusions and infidelity can be one of them. Given the history and symptoms aren’t mentioned clearly in the question description, it’s difficult to comment on the diagnosis or differentials. Treatment approaches for both the conditions differ.

Hello Othello syndrome or morbid jealousy and mania are two different conditions. Othello syndrome is a delusion and can occur in various psychiatric and organic disorders. While Mania comes under bipolar disorder. Detailed history and mental status of patient is needed to diagnose it properly. You can book video consultation from my profile here on practo so we can help the patient. Thank you.