Vimentin is an intermediate filament protein present in cells of mesenchymal origin. A number of tumors coexpress vimentin and cytokeratin eg, thyroid carcinomas, pleomorphic adenomas of the salivary glands, and some renal carcinomas. Coexpression of desmin and vimentin has also been reported in a number of soft tissue tumors eg, rhabdomyosarcomas, leiomyosarcomas and alveolar soft tissue sarcomas. Vimentin is a protein that in humans is encoded by the VIM gene. Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. All IF proteins are expressed in a highly developmentally-regulated fashion vimentin is the major cytoskeletal component of mesenchymal cells.
No special preparation is needed for IHC Marker Vimentin Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing IHC Marker Vimentin Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||A positive staining is seen in case of detection of Mesenchymal Origin Tumor|