Thyroxine Binding Globulin

Thyroxine binding globulin (TBG) is the high-affinity serum binding protein for thyroxine and triiodothyronine. Normally, the thyroid adjusts to changing concentrations of TBG by producing more or less thyroid hormone to maintain a constant level of metabolically important free hormone. Elevated TBG levels are associated with influences such as pregnancy, genetic predisposition, oral contraceptives, and estrogen therapy. TBG levels can decrease with androgenic or anabolic steroids, large doses of glucocorticoids, hypoproteinemic states, liver disease, nephrotic syndrome, and congenital TBG variants.

No special preparation is needed for Thyroxine Binding Globulin. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Thyroxine Binding Globulin. Your doctor depending on your condition will give specific instructions.