This marker can be used to aid in the diagnosis and/or prognosis of cancer. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist. This antibody recognizes the alpha-smooth muscle isoform of actin. It shows no crossreaction with actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial). A synthetic peptide corresponding to N-terminus of human Alpha-actin was used as immunogen. Smooth Muscle Actin stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary glands are also stained as they also contain actin. This MAb is reportedly useful for identifying tumors arising from smooth muscle and myoepithelial cells.
No special preparation is needed for IHC Marker SMA Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing IHC Marker SMA Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|All age groups
|A positive staining is seen in case of detection of Smooth Muscle Origin Tumors