|

Practo

Diagnostic Tests

Pseudo Cholinesterase

image

Pseudo Cholinesterase

Also known as Pseudo Cholinesterase Blood
Why book with us?
image
Home sample collection for FREE
A certified professional will collect your sample from a location of your preference.
image
Practo Powered Labs
Certified labs to ensure highest accuracy of your reports.
image
Digital reports
Access your reports anytime on your Practo account. We will email you a copy.
image
Offers and affordable prices
Get great discounts and offers on tests and packages.

What is this test?

Serum cholinesterase, often called pseudocholinesterase (PCHE), is distinguished from acetylcholinesterase or "true cholinesterase," by both location and substrate. Acetylcholinesterase is found in erythrocytes, in the lungs and spleen, in nerve endings, and in the gray matter of the brain. It is responsible for the hydrolysis of acetylcholine released at the nerve endings to mediate transmission of the neural impulse across the synapse. PCHE, the serum enzyme, is also found in liver, pancreas, heart, and white matter. Its biological role is unknown. The organophosphorus-containing insecticides are potent inhibitors of the true cholinesterase and also cause depression of PCHE. Low values of PCHE are also found in patients with liver disease. In general, patients with advanced cirrhosis and carcinoma with metastases will show a 50% to 70% decrease. Essentially normal values are seen in chronic hepatitis, mild cirrhosis, and obstructive jaundice. PCHE metabolizes the muscle relaxants succinylcholine and mivacurium, and therefore, alterations in PCHE will influence the physiologic effect of these drugs. In normal individuals (approximately 94% of the population) certain drugs and other agents, such as dibucaine and fluoride, will almost completely inhibit the PCHE activity. A small number of individuals (<1% of the population) have been shown to have genetic variants of the enzyme, and cannot metabolize the muscle relaxants succinylcholine and mivacurium and experience prolonged apnea. These individuals generally have low levels of PCHE, which is not inhibited by dibucaine or fluoride. These individuals are either homozygotes or compound heterozygotes for an atypical gene(s) controlling PCHE.

Test Preparation

No special preparation is needed for Pseudo Cholinesterase. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Pseudo Cholinesterase. Your doctor depending on your condition will give specific instructions.

Understanding your test results

GenderAge groupsValue
UNISEXAll age groups8 - 18U/ml
Your Cart0 Tests
Proceed to Checkout

Popular Health Checkup Packages

Thousands of Happy Customers

Very professional phlebo. Excellent job in collecting the sample. No pain at all. Got my report also within 24 hours.
Malathi Ganapathy
Everything went very well and smoothly. Technician was right on time. Really happy with the service.
Ashish Garnaik
Good service, Practo is avoiding to stand in que for health checkup.
Lalita Hegde
We serve in
Bangalore, Hyderabad, Chennai, Mumbai, Delhi, Pune, Kolkata, Navi Mumbai, Thane,  Gurgaon, Noida, Ahmedabad, Chandigarh, Ghaziabad, Indore, Jaipur, Lucknow,  Patna, Ernakulam, Bhubaneswar and Coimbatore.
This site is protected by reCAPTCHA and the Google  Privacy Policy and Terms of Service apply.