Metanephrines

Normetanephrine (NM) and metanephrine (MN) are the extra-neuronal catechol-o-methyl transferase (COMT) metabolites of the catecholamines norepinephrine and epinephrine, respectively. Measurement of plasma metanephrines is more sensitive (but may be less specific) than measurement of catecholamines for the detection of pheochromocytoma. Other pre-analytical factors e.g., stress, severe congestive heart failure, myocardial infarction that influence release of catecholamines and metanephrines.

No special preparation is needed for Metanephrines. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Metanephrines. Your doctor depending on your condition will give specific instructions.