Lupus anticoagulant (LA) are members of a family of antibodies with phospholipid specificity. LA may be defined as an immunoglobulin(s), IgG or IgM or a mixture of both, that interfere with one or more of the invitro phospholipid (PL) dependent tests of coagulation (i.e. aPTT). These antibodies are not associated with a hemorrhagic diathesis, but rather have been linked to thrombotic events. It is not known whether the antibody is causative, coincidental or a consequence of the thrombosis. In addition to thrombosis, other clinical complications have been associated with the presence of LA. These include strokes, non-bacterial thrombotic endocarditis, livedo reticularis and a variety of obstetrical complications such as intrauterine fetal death, recurrent spontaneous abortion, fetal growth retardation, and early onset preeclampsia.
No special preparation is needed for LA. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing LA. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Clotting time is prolonged in these tests|