Insulin-like growth factor I (IGF-I, or somatomedin C), a protein involved in stimulating somatic growth, is regulated principally by growth hormone (GH) and nutritional intake. IGF-I is transported in serum by several proteins; this helps maintain relatively high IGF-I plasma levels and minimizes fluctuations in serum IGF-I concentrations. IGF-I is useful in several growth-related disorders. Dwarfism caused by deficiency of growth hormone (hypopituitarism) results in decreased serum levels of IGF-I, while acromegaly (growth hormone excess) results in elevated levels of IGF-I. IGF-I measurements are also helpful in assessing nutritional status; levels are reduced in undernutrition and restored with a proper diet.
No special preparation is needed for IGF 1. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing IGF 1. Your doctor depending on your condition will give specific instructions.
Gender | Age groups | Value |
MALE | 11 years - 18 years | 144 - 673ng/ml |
FEMALE | 11 years - 18 years | 147 - 646ng/ml |