Hemosiderin may be seen in anemias caused by red cell destruction. Hemosiderin is found as yellow-brown granules that are free or in epithelial cells and occasionally in casts in an acidic or neutral urine. When the plasma hemoglobin level is >50 to 200 mg/dL after hemolysis, the capacity of haptoglobin to bind hemoglobin is exceeded, and hemoglobin readily passes through the glomeruli of the kidney. Part of the hemoglobin is absorbed by the proximal tubular cells where the hemoglobin iron is converted to hemosiderin. When these tubular cells are later shed into the urine, hemosiderinuria results. If all of the hemoglobin cannot be absorbed into the tubular cells, hemoglobinuria results.
No special preparation is needed for Hemosiderin Microscopy Random Urine. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Hemosiderin Microscopy Random Urine. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Normally absent in Urine and results will be positive if it is detected|