DHEA Sulphate Paediartic

This test is used to check for the genes associated with the production of dehydroepiandrosterone in young boys and girls. Dehydroepiandrosterone is a precursor sex hormone secreted by the adrenal glands present on the top of kidneys in an individual.

What is Dehydroepiandrosterone?

Dehydroepiandrosterone is secreted by the adrenal glands in the body. It is a hormone found in both men and women, which plays a role in the maturity and development of secondary sexual characteristics in adults. The hormone is converted into testosterone in men and estrogen in women. The hormone levels peak in adults by the age of 25- 30 and decrease gradually. The increased secretion of this hormone in young individuals (boys below the age of 10 yrs) causes precocious (early) puberty, the symptoms include deepening of the voice, early maturation of bones leading to shorter adult height, etc. The increased secretion of this hormone in women may cause the development of facial hair, irregular or painful menstrual periods, etc. Increased secretion of dehydroepiandrosterone in the body can occur due to genetic factors which may be inherited from the parent to the child which can be checked using various laboratory techniques.

Why is this test recommended?

This test is recommended if your doctor suspects diseases or conditions like Adrenal insufficiency (adrenal glands do not produce enough steroid hormones), Male hypogonadism (decreased testosterone in adult men), polycystic ovarian syndrome (PCOS), Hirsutism (excess of facial hair in women), amenorrhea (absence or late menstruation), etc.

Your doctor may recommend this test if you experience certain signs and symptoms like the development of facial hair and absence of menstrual periods in women, development of secondary sexual characteristics like deepening of the voice, development facial and body hair in boys below the age of 10 years, etc.

Increased blood levels of Dehydroepiandrosterone in young boys below 10 years of age may indicate precocious puberty (early puberty).

Increased concentrations of Dehydroepiandrosterone in women may indicate conditions like polycystic ovarian syndrome (PCOS), Hirsutism(excess of facial hair in women), amenorrhea (absence or late menstruation), etc.

Elevated levels of Dehydroepiandrosterone in adults can also be found in conditions like adrenal insufficiency, adrenal tumours, adrenal hyperplasia, etc.

No medical interventions are necessary if the test results are within the normal range, however, your doctor may recommend further diagnostic tests if necessary.