This test is used to determine the concentration of cyclosporine in the blood sample of an individual. This medicine is usually prescribed with other medicines during organ transplant therapies or auto-immune diseases.
What is Cyclosporin?
Cyclosporine / Cyclosporin is a type of medicine which reduces the activity of the immune system of an individual. The medicine is an extract of Tolypocladium inflatum (It is a type of fungus). It acts by selectively inhibiting T-lymphocyte cells and other components like interleukin-2, T-suppressor cells, etc. Use of this medicine is recommended by the healthcare professional for individuals undergoing solid organ transplantations, and certain autoimmune diseases like Crohn's disease, psoriasis, nephrotic syndrome, rheumatoid arthritis, etc.
What is Cyclosporine C0?
The initial concentration of medicine present in the blood of an individual before the administration of the next dose of cyclosporine following the previous dose of administration is called C0. The concentrations of this medicine are frequently evaluated in individuals to provide the appropriate dose adjustments for the treatment of autoimmune diseases, avoiding the rejection of transplanted organs, etc.
Why is this test done?
This test is used to detect the concentration of cyclosporine in the blood. The medicine has a very narrow therapeutic window (safe treatment concentration) and tends to change between individuals. Patients undergoing this therapy are frequently monitored as the effective therapeutic concentrations and excretion rates tend to vary within time to time in the same individual which may lead to complications like graft rejection or side effects related to the medicine like kidney, liver failure, high blood pressure, etc.
The individual using this medicine may develop infections very easily it reduces overall immunity. Certain medicines/diseases/conditions may interfere with the test results. It is recommended to discuss all the essential information with your doctor before undergoing this test.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Cyclosporin C0 Blood. Your doctor will give specific instructions depending on your condition on how to prepare for Cyclosporin C0 Blood.
The test results are useful in maintaining and modifying the medicine dose according to the conditions of the patient. Based on the test results your doctor will recommend appropriate changes in treatment, dosing, and frequency of the medicine.