|

Practo

Diagnostic Tests

Ck 19 Immunohistochemistry Biopsy Tissue

image

Ck 19 Immunohistochemistry Biopsy Tissue

Why book with us?
image
Home sample collection for FREE
A certified professional will collect your sample from a location of your preference.
image
Practo Associate Labs: Labs with industry standards
To ensure the accuracy of reports.
image
Digital reports
Access your reports anytime on your Practo account. We will email you a copy.
image
Offers and affordable prices
Get great discounts and offers on tests and packages.

What is this test?

CK19 reacts with the rod domain of human keratin 19, a 40 kDa polypeptide. The antibody reacts with MCF-7 cells and has been shown to label trichoblastoma, thyroid tumors, oral cancer, and epithelial odontogenic tumors. CK19 is not expressed in most hepatocytes, therefore Cytokeratin 19 is useful in the identification of liver metastasis and can be used in a panel with Hepatocyte Specific Antigen. Cytokeratin immunostaining forms the bedrock of the immunohistochemical evaluation of tumors. Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. CK19 immunohistochemistry has been used successfully in thyroid tumors to recognize papillary carcinomas for some time. However, its use in the pancreas, liver, and gastrointestinal tract (GIT) has only recently come to the fore. The purpose of this review is to look at the use of CK19 immunohistochemistry in tumors occurring at these sites. CK19 has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis. It is recommended that CK19 be part of the immunohistochemical panel in the work-up of pancreatic endocrine tumors. CK19 is positive in the most of neuroendocrine tumors occurring in the rest of the GIT, except rectal tumors, which are negative. In the liver, CK19 is of prognostic value in hepatocellular carcinomas and is of use in distinguishing cholangiocarcinoma from hepatocellular carcinomas. It can also be used to highlight native ductules in the liver and helps separate conditions such as focal nodular hyperplasia from hepatic adenoma. The vast majority of adenocarcinomas in the GIT and pancreas are CK19 positive.

Also known as Cytokeratin 19 Immunohistochemistry Biopsy Tissue.

Test Preparation

No special preparation is needed for Ck 19 Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Ck 19 Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.

Understanding your test results

GenderAge groupsValue
UNISEXAll age groupsTest is positive if the conditions listed are detected
Your Cart0 Tests
Proceed to Checkout

Popular Health Checkup Packages

Thousands of Happy Customers

Very professional phlebo. Excellent job in collecting the sample. No pain at all. Got my report also within 24 hours.
Malathi Ganapathy
Everything went very well and smoothly. Technician was right on time. Really happy with the service.
Ashish Garnaik
Good service, Practo is avoiding to stand in que for health checkup.
Lalita Hegde
We serve in
Bangalore, Hyderabad, Chennai, Mumbai, Delhi, Pune, Kolkata, Navi Mumbai, Thane,  Gurgaon, Noida, Ahmedabad, Chandigarh, Ghaziabad, Indore, Jaipur, Lucknow,  Patna, Ernakulam, Bhubaneswar and Coimbatore.
This site is protected by reCAPTCHA and the Google  Privacy Policy and Terms of Service apply.