CD79b molecule, immunoglobulin-associated beta, also known as CD79B is a human gene. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. Anti-CD79b for its usefulness in the diagnosis of B-cell chronic lymphoproliferative disorders (BCLPDs), particularly chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). We analyzed 100 BCLPDs for CD5, CD19, CD20, CD23, CD79b, and surface immunoglobulin light chain (sIg) expression by 4-color flow cytometry. CD20, CD79b, and sIg expression were quantified.
No special preparation is needed for Cd 79B Immunohistochemistry Bone Marrow. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Cd 79B Immunohistochemistry Bone Marrow. Your doctor depending on your condition will give specific instructions.
|All age groups
|Test is positive if the conditions listed are detected